4,4'-Methylenebis(2-methoxyphenol) CAS 3888-22-0
| CAS No. | 3888-22-0 |
| Molecular Formula | C11H5F17O |
| Molecular Weight | 476.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4,4'-Methylenebis(2-methoxyphenol) (CAS 3888-22-0) is a high-purity analytical reference standard with the molecular formula C11H5F17O and a molecular weight of 476.13 g/mol.
The molecular framework of 4,4'-Methylenebis(2-methoxyphenol) (C11H5F17O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 4,4'-Methylenebis(2-methoxyphenol) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H5F17O |
| Molecular Weight | 476.13 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F-containing |
Related Methylenebis Standards
- 3,3'-(Methylenebis(thiazole-2,4-diyl))bis(2H-chromen-2-one) (CAS 319491-51-5)
- 2,2'-methylenebis[(4 <I> R </I> ,5 <I> S </I>)-4,5-diphenyl-2-oxazoline] (CAS 139021-82-2)
- 6,6'-Methylenebis(2-(2-hydroxy-5-methylbenzyl)-4-methylphenol) (CAS 20837-68-7)
- (Methylenebis(2-hydroxy-4-methoxy-5,1-phenylene))bis(phenylmethanone) (CAS 68716-15-4)
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- 4,4′-[Methylenebis(4,1-phenylenenitrilomethylidyne)]bis[2-methoxyphenol] (CAS 67727-63-3)
- 4,4-Methylenebis(3-chlorophenyl) diisothiocyanate (CAS 206761-69-5)
Recommended Standards
- (1H,1H-Perfluorononyl)oxirane (CAS 38565-53-6)
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- 5-Bromo-3-iodo-1-tosyl-1H-indole (CAS 142688-28-6)
- 5-(2,4-Dichlorophenoxy)-3-(3,4-dichlorophenyl)-[1,2,4]triazolo[4,3-c]quinazoline (CAS 477853-53-5)
- 5-Amino-2-(methylthio)thiazole-4-carboxamide (CAS 52868-69-6)
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- trans-Methyl 3-amino-2,2-dimethylcyclobutanecarboxylate hydrochloride (CAS 1392804-19-1)
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- N-((3-(2-Aminoethyl)-1,2,4-oxadiazol-5-yl)methyl)acetamide (CAS 1706449-22-0)
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