4-Hydroxy-2-(trifluoromethyl)benzoic Acid CAS 320-32-1
| CAS No. | 320-32-1 |
| Molecular Formula | C8H5F3O3 |
| Molecular Weight | 206.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 4-Hydroxy-2-(trifluoromethyl)benzoic Acid (CAS 320-32-1), a certified reference material (molecular formula C8H5F3O3, MW 206.12 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 4-Hydroxy-2-(trifluoromethyl)benzoic Acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 206.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5F3O3 |
| Molecular Weight | 206.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Hydroxy Standards
- 4-Hydroxy-2-(trifluoromethoxy)benzaldehyde (CAS 1017083-37-2)
- 2-Hydroxy-4-(trifluoromethoxy)benzaldehyde (CAS 1071156-25-6)
- 2-Hydroxy-6-(trifluoromethyl)nicotinamide (CAS 116548-03-9)
- 3-Hydroxy-4-(trifluoromethoxy)benzaldehyde (CAS 1208078-41-4)
- 2-Hydroxy-2-(2,3,4-trifluorophenyl)acetic acid (CAS 1214332-27-0)
- 5-Hydroxy-2-(trifluoromethyl)benzoic acid (CAS 1243373-31-0)
- 2-Hydroxy-6-(trifluoromethoxy)benzaldehyde (CAS 1261500-70-2)
- 5-Hydroxy-2-(trifluoromethoxy)benzaldehyde (CAS 1261584-14-8)
Recommended Standards
- 4-Bromo-N,N-dimethylcyclohexanamine (CAS 859178-97-5)
- 4-Hydroxy-3-(trifluoromethoxy)benzaldehyde (CAS 53104-95-3)
- 4-(3-Bromopropyl)piperidine (CAS 256409-16-2)
- 4-Hydroxy-3-(trifluoromethyl)benzoic Acid (CAS 220239-68-9)
- N,N-Dimethyl-3-nitroaniline (CAS 619-31-8)
- 2-Mercaptobenzothiazole Zinc Salt (CAS 155-04-4)
- 4-Amino-n-(3-bromo-4-ethoxyphenyl)benzenesulfonamide (CAS 156782-94-4)
- Bolfortan (CAS 668-56-4)
- 8-Bromo-4-methylcinnoline (CAS 1092287-69-8)
- 67715-80-4 40P17KW8WL 2-Methyl-4-propyl-1,3-oxathiane 1,3-Oxathiane, 2-methyl-4-propyl- FEMA No. 3578 UNII-40P17KW8WL (CAS 67715-80-4)
- 4-Ethoxy-1-ethyl-1h-indole-2-carboxylic acid (CAS 1017062-78-0)
- Ethyl 2-oxo-2-(m-tolyl)acetate (CAS 66644-68-6)
- Fmoc-Val-Ala-PAB-OH (CAS 1394238-91-5)
- D-Lys20-Tirzepatide (CAS CATO-CPTD788914)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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