(4Z)-2-[(4-Chlorophenyl)methoxy]-4-{[(4-methoxyphenyl)amino]methylidene}-1,2,3,4-tetrahydroisoquinoline-1,3-dione CAS 320420-24-4
| CAS No. | 320420-24-4 |
| Molecular Formula | C24H19ClN2O4 |
| Molecular Weight | 434.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (4Z)-2-[(4-Chlorophenyl)methoxy]-4-{[(4-methoxyphenyl)amino]methylidene}-1,2,3,4-tetrahydroisoquinoline-1,3-dione (C24H19ClN2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
(4Z)-2-[(4-Chlorophenyl)methoxy]-4-{[(4-methoxyphenyl)amino]methylidene}-1,2,3,4-tetrahydroisoquinoline-1,3-dione (CAS 320420-24-4) is a high-purity analytical reference standard with the molecular formula C24H19ClN2O4 and a molecular weight of 434.87 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (4Z)-2-[(4-Chlorophenyl)methoxy]-4-{[(4-methoxyphenyl)amino]methylidene}-1,2,3,4-tetrahydroisoquinoline-1,3-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H19ClN2O4 |
| Molecular Weight | 434.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- benzyl 4-(5-chloro-1-(2-ethoxy-2-oxoethyl)-6-oxo-1,6-dihydropyridazin-4-yl)piperazine-1-carboxylate (CAS 1000018-18-7)
- Avanafil Impurity 47 (CAS CATO-C4X-111847)
- Avanafil Impurity 49 (CAS CATO-C4X-111849)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-N-(3,4-dimethoxyphenethyl)acetamide (CAS 1023543-68-1)
- 3-(2-Chlorophenyl)-5-methyl-N-octylisoxazole-4-carboxamide (CAS 543715-03-3)
- 2-(2,4-Difluorophenyl)-1,3,4-oxadiazole (CAS 1171930-30-5)
- 2-(2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)propanoic acid (CAS 2089712-60-5)
- (2E)-2-(4-Chlorophenyl)-3-[(3-chlorophenyl)amino]prop-2-enenitrile (CAS 338403-08-0)
- 2,2-Dibromo-1-(3-nitrophenyl)ethan-1-one (CAS 13651-07-5)
- Cyhalothrin Impurity 15 (CAS 71962-66-8)
- Ethyl 6,8-dibromo-2-oxo-2H-chromene-3-carboxylate (CAS 2199-89-5)
- 3-Bromo-4-(4-fluorophenoxy)benzenesulfonamide (CAS 1282732-14-2)
- 3-Ethyl-2-((3-methoxybenzyl)thio)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one (CAS 578754-04-8)
- Cholecystokinin Octapeptide (1-4) (desulfated) (CAS 80790-40-5)
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