2-(2-(2-Chlorophenyl)-4-phenylthiazol-5-yl)-N-(4-methoxyphenyl)acetamide CAS 338957-27-0

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2-(2-Chlorophenyl)-4-phenylthiazol-5-yl)-N-(4-methoxyphenyl)acetamide.

2-(2-(2-Chlorophenyl)-4-phenylthiazol-5-yl)-N-(4-methoxyphenyl)acetamide (CAS 338957-27-0), molecular formula C24H19ClN2O2S and molecular weight 434.94 g/mol, is a CATO reference standard with documented purity and traceability.

2-(2-(2-Chlorophenyl)-4-phenylthiazol-5-yl)-N-(4-methoxyphenyl)acetamide (C24H19ClN2O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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