3-[(E)-2-[(2,4-Difluorophenyl)amino]-1-nitroethenyl]-1,3-dihydro-2-benzofuran-1-one CAS 320420-45-9
| CAS No. | 320420-45-9 |
| Molecular Formula | C16H10F2N2O4 |
| Molecular Weight | 332.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-[(E)-2-[(2,4-Difluorophenyl)amino]-1-nitroethenyl]-1,3-dihydro-2-benzofuran-1-one.
CATO supplies 3-[(E)-2-[(2,4-Difluorophenyl)amino]-1-nitroethenyl]-1,3-dihydro-2-benzofuran-1-one (CAS 320420-45-9), a certified reference material (molecular formula C16H10F2N2O4, MW 332.26 g/mol) for analytical method development and quality control.
3-[(E)-2-[(2,4-Difluorophenyl)amino]-1-nitroethenyl]-1,3-dihydro-2-benzofuran-1-one (C16H10F2N2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-[(E)-2-[(2,4-Difluorophenyl)amino]-1-nitroethenyl]-1,3-dihydro-2-benzofuran-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H10F2N2O4 |
| Molecular Weight | 332.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- 5-Chloro-1-tosyl-1H-pyrrolo[2,3-b]pyridine (CAS 1417422-02-6)
- Methyl 2-amino-4-bromo-5-fluoro-3-methylbenzoate (CAS 1878216-32-0)
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- 4-Phenylpiperidine Hydrochloride (CAS 10272-49-8)
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- Lixisenatide (CAS 320367-13-3（free base）)
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