1-[(3,4-Difluorophenyl)methyl]-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamide CAS 338977-73-4
| CAS No. | 338977-73-4 |
| Molecular Formula | C14H9F5N2O2 |
| Molecular Weight | 332.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-[(3,4-Difluorophenyl)methyl]-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamide (CAS 338977-73-4), molecular formula C14H9F5N2O2 and molecular weight 332.23 g/mol, is a CATO reference standard with documented purity and traceability.
1-[(3,4-Difluorophenyl)methyl]-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamide (C14H9F5N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 1-[(3,4-Difluorophenyl)methyl]-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H9F5N2O2 |
| Molecular Weight | 332.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluorophenyl Standards
- 2-((3-(3,5-Difluorophenyl)-2-oxo-2h-chromen-7-yl)oxy)acetic acid (CAS 951999-09-0)
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Recommended Standards
- 1-(4-Bromophenyl)-3-((4-ethylphenyl)amino)propan-1-one (CAS 423735-02-8)
- 1-Benzyl-3-(4-bromophenoxy)pyrrolidine (CAS 337912-63-7)
- 1-(4-Bromophenyl)-3-((3,4-dimethylphenyl)amino)propan-1-one (CAS 423733-46-4)
- 2-(2-Bromophenyl)-N-(2-phenylpropan-2-yl)acetamide (CAS 76440-32-9)
- 1-(2-Benzyloxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole (CAS 1562305-15-0)
- 6-Chloro-3-(2,2,6,6-tetramethylpiperidin-4-yl)-3,4-dihydro-2H-[1,3]oxazino[5,6-h]quinoline (CAS 380192-95-0)
- tert-Butyl 3-phenylpyrrolidine-1-carboxylate (CAS 147410-43-3)
- 3-(4-Fluorobenzyl)-2-thioxo-2,3-dihydroquinazolin-4(1h)-one (CAS 431980-10-8)
- N-(2-{5-[(4-tert-butylphenyl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl}ethyl)-2-chloroacetamide (CAS 565195-76-8)
- 5-Chloro-3-hydrazinylpyridazin-4-amine (CAS 53180-75-9)
- 2-((4-Methyl-5-(((3-nitrophenyl)amino)methyl)-4H-1,2,4-triazol-3-yl)thio)acetohydrazide (CAS 1119449-47-6)
- 2H,3H,5H,6H,7H-[1,3]Thiazolo[3,2-a]pyrimidin-3-one (CAS 92897-32-0)
- Methyl 6-acetyl-3,5-diaminopyrazine-2-carboxylate (CAS 135673-70-0)
- Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 75976-10-2)
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