4'-Chloro-2,2,2-trifluoroacetophenone CAS 321-37-9
| CAS No. | 321-37-9 |
| Molecular Formula | C8H10ClF3O |
| Molecular Weight | 214.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4'-Chloro-2,2,2-trifluoroacetophenone.
CATO supplies 4'-Chloro-2,2,2-trifluoroacetophenone (CAS 321-37-9), a certified reference material (molecular formula C8H10ClF3O, MW 214.61 g/mol) for analytical method development and quality control.
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 4'-Chloro-2,2,2-trifluoroacetophenone is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 214.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4'-Chloro-2,2,2-trifluoroacetophenone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H10ClF3O |
| Molecular Weight | 214.61 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-Chloro-N-(2-nitrophenyl)acetamide (CAS 10147-70-3)
- 2-Chloro-n-(3-nitrophenyl)acetamide (CAS 10147-71-4)
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Recommended Standards
- 2251-65-2 3-(TRIFLUOROMETHYL)BENZOYL CHLORIDE 3-(TRIFLUOROMETHYL)BENZYOL CHLORIDE 3-(Trifluoromethyl) benzoyl chloride ALPHA,ALPHA,ALPHA-TRIFLUORO-M-TOLUOYL CHLORIDE ALPHA,ALPHA,ALPHA-TRIFLUORO-M-TOLYL CHLORIDE AS01916 BENZOYL CHLORIDE, 3-(TRIFLUOROMETHYL)- LABOTEST-BB LT03379715 LABOTEST-BB LTBB005353 M-TRIFLUOROMETHYLBENZOYL CHLORIDE MTF-BOC TIMTEC-BB SBB006693 (CAS 2251-65-2)
- 2-(TRIFLUOROMETHYL)BENZOYL CHLORIDE 329-15-7 4-(TRIFLUOROMETHYL)BENZOYL CHLORIDE 4-(TRIFLUOROMETHYL)BENZYOL CHLORIDE ALPHA,ALPHA,ALPHA-TRIFLUORO-O-TOLUOYL CHLORIDE ALPHA,ALPHA,ALPHA-TRIFLUORO-P-TOLUOYL CHLORIDE AS00061 O-TRIFLUOROMETHYLBENZOYL CHLORIDE OTAVA-BB 1051756 OTF-BOC PTF-BOC TIMTEC-BB SBB003467 TIMTEC-BB SBB006689 TRIFLUORO-O-TOLUOYL CHLORIDE p-Trifluoromethylbenzoyl chloride (CAS 329-15-7)
- N-(5-Chloro-2-nitrophenyl)acetamide (CAS 5443-33-4)
- 2-Chloro-5-(trifluoromethyl)benzaldehyde 2-chloro-5-trifluoromethylbenzaldehyde 2-chloro-5-trifluoromethyl benzaldehyde 2-chloro-5-trifluoromethyl-benzaldehyde 2-chloro-5-(trifluoromethyl) benzaldehyde 82386-89-8 (CAS 82386-89-8)
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Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com