Duloxetine EP Impurity G CAS 321-38-0
| CAS No. | 321-38-0 |
| Molecular Formula | C10H7F |
| Molecular Weight | 146.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Duloxetine EP Impurity G is closely related to fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Duloxetine EP Impurity G (CAS 321-38-0, C10H7F) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Duloxetine EP Impurity G (C10H7F) contains fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Duloxetine EP Impurity G under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7F |
| Molecular Weight | 146.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Duloxetine Standards
- Duloxetine EP Impurity D (CAS 90-15-3)
- Duloxetine Impurity 55 (CAS 1045348-04-6)
- Duloxetine Impurity 47 (CAS 22176-00-7)
- Duloxetine EP Impurity B (CAS 116539-55-0)
- Duloxetine Impurity (CAS 116539-57-2)
- Duloxetine Impurity 46 (CAS 2230525-46-7)
- Duloxetine Impurity 10 (CAS 638-32-4)
- Duloxetine Impurity 9 (CAS 110-14-5)
Recommended Standards
- 347-54-6 5-FLUOROSALICYLALDEHYDE 5-Fluoro-2-hydroxybenzaldehyde ART-CHEM-BB ACB000519 AS01457 PHARMABRIDGE P-2996 (CAS 347-54-6)
- 2-Fluoronaphthalene (CAS 323-09-1)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com