Methyl 4-(Difluoromethoxy)-3-fluorobenzoate CAS 321198-19-0
| CAS No. | 321198-19-0 |
| Molecular Formula | C9H7F3O3 |
| Molecular Weight | 220.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 220.15 g/mol gives Methyl 4-(Difluoromethoxy)-3-fluorobenzoate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Methyl 4-(Difluoromethoxy)-3-fluorobenzoate (CAS 321198-19-0), molecular formula C9H7F3O3 and molecular weight 220.15 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Methyl 4-(Difluoromethoxy)-3-fluorobenzoate (C9H7F3O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 220.15 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Methyl 4-(Difluoromethoxy)-3-fluorobenzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7F3O3 |
| Molecular Weight | 220.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
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Recommended Standards
- Methyl 3-hydroxy-5-(trifluoromethyl)benzoate (CAS 796119-63-6)
- Methyl 4-(Trifluoromethoxy)benzoate (CAS 780-31-4)
- Methyl 3-amino-5-(trifluoromethyl)picolinate (CAS 866775-17-9)
- Methyl 4-hydroxy-2-(trifluoromethyl)benzoate (CAS 790695-49-7)
- 2-(((tert-Butyldimethylsilyl)oxy)methyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine (CAS 2760431-07-8)
- Ala(CN)5-Somatostatin (CAS CATO-CPTD788780)
- 4-Chloro-2-(2-chlorophenyl)-1H-imidazo[4,5-c]pyridine (CAS 77712-91-5)
- 2-Bromo-1-((2R,5S)-2,5-dimethylpyrrolidin-1-yl)ethanone (CAS 157905-03-8)
- Methyl 4-chloro-3-(pyrrolidin-1-yl)benzoate (CAS 151296-58-1)
- 1-(azidomethyl)-2-(trifluoromethyl)benzene (CAS 823189-03-3)
- [5-(difluoromethyl)-3-pyridyl]boronic acid (CAS 1382475-69-5)
- Dapoxetine Impurity 27 (CAS 82769-75-3)
- 2-Amino-6-bromopyrido[2,3-d]pyrimidine (CAS 882670-89-5)
- D-[Ser]8-Liraglutide (CAS CATO-C4X-199238)
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