[(3Z)-5-Methyl-2-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-2,3-dihydro-1H-indol-3-ylidene]amino 3-methylbutanoate CAS 321430-05-1
| CAS No. | 321430-05-1 |
| Molecular Formula | C22H21F3N2O3 |
| Molecular Weight | 418.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of [(3Z)-5-Methyl-2-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-2,3-dihydro-1H-indol-3-ylidene]amino 3-methylbutanoate (C22H21F3N2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
[(3Z)-5-Methyl-2-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-2,3-dihydro-1H-indol-3-ylidene]amino 3-methylbutanoate (CAS 321430-05-1) is a high-purity analytical reference standard with the molecular formula C22H21F3N2O3 and a molecular weight of 418.41 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), [(3Z)-5-Methyl-2-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-2,3-dihydro-1H-indol-3-ylidene]amino 3-methylbutanoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H21F3N2O3 |
| Molecular Weight | 418.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- 2,4-Dibromo-6-(trifluoromethoxy)benzene-1-sulfonyl chloride (CAS 1208075-27-7)
- [(3Z)-5-Methyl-2-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-2,3-dihydro-1H-indol-3-ylidene]amino pentanoate (CAS 321430-01-7)
- Reproterol impurity 1 (CAS CATO-C4X-30991)
- Regadenoson Impurity 31 (CAS CATO-C4X-198531)
- 2-Methoxyhexan-1-amine (CAS 1466958-56-4)
- 7-Bromo-5-(2-fluorophenyl)-4,5-dihydro-1H-benzo[e][1,4]diazepin-2(3H)-one (CAS 1799-13-9)
- (2,3-Dimethoxy-benzyl)-(2-fluoro-5-methoxy-benzyl)-pyridin-2-ylmethyl-amine (CAS 883549-47-1)
- 2-(3-Chlorophenyl)isoindolin-1-imine (CAS 321686-44-6)
- 2-((2,6-Dichlorobenzyl)thio)-4,6-diphenylnicotinonitrile (CAS 400738-16-1)
- Ethyl 5-bromo-4-(trifluoromethyl)-1H-imidazole-2-carboxylate (CAS 2105692-01-9)
- 3-(1-(4-Fluorophenyl)-1H-pyrrol-2-yl)-3-oxopropanenitrile (CAS 1403568-08-0)
- (2,6-Diethyl-4-methylphenyl)boronic acid (CAS 953075-90-6)
- tert-Butyl ((1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-yl)methyl)(methyl)carbamate (CAS 1354023-96-3)
- Semaglutide impurity 258 (CAS CATO-C4X-2226258)
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