2-((2,6-Dichlorobenzyl)thio)-4,6-diphenylnicotinonitrile CAS 400738-16-1
| CAS No. | 400738-16-1 |
| Molecular Formula | C25H16Cl2N2S |
| Molecular Weight | 447.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-((2,6-Dichlorobenzyl)thio)-4,6-diphenylnicotinonitrile.
2-((2,6-Dichlorobenzyl)thio)-4,6-diphenylnicotinonitrile (CAS 400738-16-1) is a high-purity analytical reference standard with the molecular formula C25H16Cl2N2S and a molecular weight of 447.38 g/mol.
2-((2,6-Dichlorobenzyl)thio)-4,6-diphenylnicotinonitrile (C25H16Cl2N2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-((2,6-Dichlorobenzyl)thio)-4,6-diphenylnicotinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H16Cl2N2S |
| Molecular Weight | 447.38 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Dichlorobenzyl Standards
- 4-(5-((3,4-Dichlorobenzyl)thio)-4-ethyl-4H-1,2,4-triazol-3-yl)-2-phenylthiazole (CAS 338759-70-9)
- 3-((2,6-Dichlorobenzyl)oxy)-N-(2,3-dichlorophenyl)thiophene-2-carboxamide (CAS 344270-16-2)
- 4-((2,4-Dichlorobenzyl)oxy)-3-ethoxy-5-iodobenzonitrile (CAS 1706445-44-4)
- (E)-1-(2,4-dichlorobenzyl)-2-(2,4-dichlorostyryl)-1H-benzo[d]imidazole (CAS 338771-83-8)
- (E)-1-(2,5-dichlorobenzyl)-2-(2,4-dichlorostyryl)-1H-benzo[d]imidazole (CAS 338771-81-6)
- 2-((2-((3,4-Dichlorobenzyl)thio)-1-methyl-1H-imidazol-5-yl)methoxy)isoindoline-1,3-dione (CAS 400088-13-3)
- 2-((2,6-Dichlorobenzyl)thio)-6-methyl-4-(thiophen-2-yl)-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carbonitrile (CAS 354556-54-0)
- 3-(2,6-Dichlorobenzyl)-2-methyl-1-(4-(phenyldiazenyl)phenyl)pyridin-4(1H)-one (CAS 400088-49-5)
Recommended Standards
- (2Z)-2-(3-Chlorophenyl)-3-(2-{[(4-chlorophenyl)methyl]sulfanyl}quinolin-3-yl)prop-2-enenitrile (CAS 478065-18-8)
- 2-(Benzylthio)-4-(2-chlorophenyl)-6-(4-chlorophenyl)nicotinonitrile (CAS 332177-30-7)
- ((2R,3S,4R,5R)-5-(6-Amino-8-((5-aminopentyl)amino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate (CAS 62209-06-7)
- 2-(Benzylthio)-4,6-bis(4-chlorophenyl)nicotinonitrile (CAS 332385-71-4)
- β-Carboline-3-carboxylic acid propyl ester (CAS 76808-18-9)
- 4-Chloro-7-(3-chloro-4-methylphenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidine (CAS 887202-25-7)
- 5-Nitrobenzothiazole (CAS 2942-07-6)
- 2-(3-Ethylphenoxy)acetic acid (CAS 1878-51-9)
- 2-Hydroxy-7-(methylthio)quinoline-3-carbaldehyde (CAS 873300-63-1)
- Cyclo(-Phe-Ser) (CAS 35591-00-5)
- Ethyl2-(Hydroxymethyl)-4-methylthiazole-5-carboxylate (CAS 1865219-65-3)
- Imidafenacin Related Compound 10 (CAS 212756-27-9)
- 3-Ethylbenzo[d]isoxazol-5-amine (CAS 69491-71-0)
- Tirzepatide Impurity 20 (CAS CATO-C4X-324020)
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