5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}thiophene-2-carbonitrile CAS 321430-92-6
| CAS No. | 321430-92-6 |
| Molecular Formula | C12H6ClF3N2S |
| Molecular Weight | 302.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}thiophene-2-carbonitrile.
CATO supplies 5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}thiophene-2-carbonitrile (CAS 321430-92-6), a certified reference material (molecular formula C12H6ClF3N2S, MW 302.70 g/mol) for analytical method development and quality control.
5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}thiophene-2-carbonitrile (C12H6ClF3N2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H6ClF3N2S |
| Molecular Weight | 302.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related chloro Standards
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-(thiophen-2-yl)acetonitrile (CAS 338407-61-7)
- 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(thiophen-3-yl)acetonitrile (CAS 338407-26-4)
- 2-CHLORO-9-CYCLOPENTYL-7,7-DIFLUORO-8,9-DIHYDRO-5H-PYRIMIDO[4,5-B][1,4]DIAZEPIN-6(7H)-ONE (CAS 1062246-01-8)
- 4-Chloro-2-(4-fluorophenyl)-6-nitroquinoline (CAS 1416440-17-9)
- 2-((6-Chloro-2-phenyl-1H-benzo[d]imidazol-1-yl)oxy)acetic acid (CAS 338978-62-4)
- 2-(5-Chloro-2-oxo-3-phenyl-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetic acid (CAS 79759-53-8)
- 2-Chloro-3-(5-(methoxymethyl)furan-2-yl)naphthalene-1,4-dione (CAS 65679-85-8)
- 2-Chloro-9-(4,4-difluorocyclohexyl)-7-methyl-7,9-dihydro-8H-purin-8-one (CAS 2408842-49-7)
Recommended Standards
- 3-(2-Chlorophenoxymethyl)-1-benzofuran-2-carboxylic acid (CAS 1039891-11-6)
- 3-[3-(Trifluoromethyl)phenoxy]propane-1-sulfonyl chloride (CAS 1340078-21-8)
- N-(3-chlorophenyl)-3-(3-nitrophenyl)acrylamide (CAS 109567-63-7)
- (Z)-EThyl 2-(2-(5-(1-methyl-4-ethoxycarbonyl-1h-pyrazole))hydrazono)-2-chloroacetate (CAS 1207062-34-7)
- 5-(Bromomethyl)-7-methoxybenzofuran (CAS 831222-79-8)
- Benzene, 1,1,1-[[[2-(bromomethyl)-2-propen-1-yl]oxy]methylidyne]tris- (CAS 510730-18-4)
- 3-Benzyl-5-bromo-1H-pyrrolo[2,3-b]pyridine (CAS 2137929-76-9)
- Plerixafor Impurity 3 (CAS CATO-C4X-11333)
- 6-(tert-Butyl)-3-((2,4-dichlorophenyl)amino)-1,2,4-triazin-5(4H)-one (CAS 898650-84-5)
- 2-Methyl-9-phenoxyacridine (CAS 61078-24-8)
- 4-Bromo-N-(2-fluorobenzyl)aniline (CAS 1019545-94-8)
- Ertugliflozin impurity 14 (CAS CATO-C4X-301114)
- Methyl (3-hydroxy-3-methylpent-4-en-1-yl)carbamate (CAS 116699-61-7)
- Semaglutide Impurity 151 xTFA (CAS CATO-C4X-2226151)
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