N-(4-chlorophenyl)-1-(2,4-difluorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide CAS 321431-62-3
| CAS No. | 321431-62-3 |
| Molecular Formula | C16H11ClF2N4O |
| Molecular Weight | 348.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-(4-chlorophenyl)-1-(2,4-difluorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N-(4-chlorophenyl)-1-(2,4-difluorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide (CAS 321431-62-3), molecular formula C16H11ClF2N4O and molecular weight 348.73 g/mol, is a CATO reference standard with documented purity and traceability.
N-(4-chlorophenyl)-1-(2,4-difluorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide (C16H11ClF2N4O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-(4-chlorophenyl)-1-(2,4-difluorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H11ClF2N4O |
| Molecular Weight | 348.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related N Standards
- Methyl 3-(4-Chlorophenyl)-1-(2,4-difluorophenyl)-1H-pyrazole-5-carboxylate (CAS 1202028-92-9)
- 1-(4-Chlorophenyl)-N-(2,4-difluorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide (CAS 321431-23-6)
- 2-(5-(4-Chlorophenyl)isoxazol-3-yl)-N-(2,4-difluorophenyl)acetamide (CAS 946316-17-2)
- 3-(2-Chlorophenyl)-N-(2,4-difluorophenyl)-5-methylisoxazole-4-carboxamide (CAS 326902-82-3)
- 4-(4-Chlorophenyl)-2-[(3-nitrophenyl)amino]-4-oxobutanoic acid (CAS 1009720-76-6)
- 4-Chlorophenyl (3Z)-3-{[(4-nitrophenyl)methoxy]imino}propanoate (CAS 338395-26-9)
- 1-(4-Chlorophenyl)-4-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline (CAS 338773-13-0)
- 3-(4-Chlorophenyl)-5-(trifluoromethyl)-[1,2,4]triazolo[4,3-c]quinazoline (CAS 303148-96-1)
Recommended Standards
- 1-(Benzo[d][1,3]dioxol-5-yl)-3-((4-chloro-3-nitrophenyl)amino)propan-1-one (CAS 892155-46-3)
- 1,1,1-Tribromo-3,3,3-trifluoropropan-2-one (CAS 431-91-4)
- Dacomitinib Impurity 39 (CAS CATO-C4X-208639)
- 3-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-7,12-dioxa-3-azaspiro[5.6]Dodec-9-ene (CAS 339110-28-0)
- 3-Amino-N-(prop-2-yn-1-yl)propanamide (CAS 1016779-97-7)
- 4-(3-bromopropyl)pyridine hydrobromide (CAS 64262-18-6)
- 5-Chloro-6-oxo-1,6-dihydropyridine-2-carbonitrile (CAS 1784430-76-7)
- 2-chloro-4H,5H-naphtho[1,2-d][1,3]thiazole (CAS 1344354-06-8)
- (Benzamido)oxy Acetic Acid (CAS 5251-93-4)
- 2-(Bromomethyl)-3-nitropyridine hydrobromide (CAS 19993-50-1)
- 5-[[3-Chloro-4-(2-cyclohexylethoxy)phenyl]methylene]-2,4-thiazolidinedione (CAS 1239610-72-0)
- Dichlorobis(ethylenediamine)nickel(II) (CAS 135759-08-9)
- 1-Benzyl-3-(5-methylisoxazol-3-yl)urea (CAS 791817-34-0)
- Anti-Inflammatory Peptide 3 (CAS 118850-73-0)
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