3-(2-Chlorophenyl)-N-(2,4-difluorophenyl)-5-methylisoxazole-4-carboxamide CAS 326902-82-3
| CAS No. | 326902-82-3 |
| Molecular Formula | C17H11ClF2N2O2 |
| Molecular Weight | 348.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 348.73 g/mol gives 3-(2-Chlorophenyl)-N-(2,4-difluorophenyl)-5-methylisoxazole-4-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-(2-Chlorophenyl)-N-(2,4-difluorophenyl)-5-methylisoxazole-4-carboxamide (CAS 326902-82-3), a certified reference material (molecular formula C17H11ClF2N2O2, MW 348.73 g/mol) for analytical method development and quality control.
3-(2-Chlorophenyl)-N-(2,4-difluorophenyl)-5-methylisoxazole-4-carboxamide (C17H11ClF2N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H11ClF2N2O2 |
| Molecular Weight | 348.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- Methyl 3-(4-Chlorophenyl)-1-(2,4-difluorophenyl)-1H-pyrazole-5-carboxylate (CAS 1202028-92-9)
- 1-(4-Chlorophenyl)-N-(2,4-difluorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide (CAS 321431-23-6)
- 2-(5-(4-Chlorophenyl)isoxazol-3-yl)-N-(2,4-difluorophenyl)acetamide (CAS 946316-17-2)
- N-(4-chlorophenyl)-1-(2,4-difluorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide (CAS 321431-62-3)
- 4-(4-Chlorophenyl)-2-[(3-nitrophenyl)amino]-4-oxobutanoic acid (CAS 1009720-76-6)
- 4-Chlorophenyl (3Z)-3-{[(4-nitrophenyl)methoxy]imino}propanoate (CAS 338395-26-9)
- 1-(4-Chlorophenyl)-4-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline (CAS 338773-13-0)
- 3-(4-Chlorophenyl)-5-(trifluoromethyl)-[1,2,4]triazolo[4,3-c]quinazoline (CAS 303148-96-1)
Recommended Standards
- 1-(Benzo[d][1,3]dioxol-5-yl)-3-((4-chloro-3-nitrophenyl)amino)propan-1-one (CAS 892155-46-3)
- Dacomitinib Impurity 39 (CAS CATO-C4X-208639)
- 1,1,1-Tribromo-3,3,3-trifluoropropan-2-one (CAS 431-91-4)
- Dacomitinib Impurity 30 (CAS CATO-C4X-208630)
- Tert-butyl (2-chloro-3-methylpyridin-4-yl)carbamate (CAS 370864-66-7)
- 1-(8-Ethoxy-2-oxo-2H-chromene-3-carbonyl)piperidine-4-carboxamide (CAS 898504-14-8)
- 41725-90-0 methyl 3-methylcyclohexa-2,5-dienecarboxylate (CAS 41725-90-0)
- 1,7-Dihydroxyanthracene-9,10-dione (CAS 569-08-4)
- 3-Amino-1-bromoisoquinoline (CAS 13130-79-5)
- 1-(tert-Butyl) 5-methyl L-glutamate (CAS 79640-72-5)
- Tolvaptan Impurity 56 (CAS CATO-C4X-195556)
- 5-((3-Nitrophenoxy)methyl)furan-2-carbohydrazide (CAS 886496-17-9)
- 4-Hydroxy-5-methyl-1,8-naphthyridin-2(1H)-one (CAS 1209781-73-6)
- [2-31]-Semaglutide C (x TFA Salt) (CAS CATO-C4X-2226118)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com