3-(4-Chlorophenyl)-1-(6-chloropyridazin-3-yl)-6-(trifluoromethyl)-1H-pyrazolo[4,3-b]pyridine CAS 321432-68-2
| CAS No. | 321432-68-2 |
| Molecular Formula | C17H8Cl2F3N5 |
| Molecular Weight | 410.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 3-(4-Chlorophenyl)-1-(6-chloropyridazin-3-yl)-6-(trifluoromethyl)-1H-pyrazolo[4,3-b]pyridine (C17H8Cl2F3N5) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 410.18 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
3-(4-Chlorophenyl)-1-(6-chloropyridazin-3-yl)-6-(trifluoromethyl)-1H-pyrazolo[4,3-b]pyridine (CAS 321432-68-2) is a high-purity analytical reference standard with the molecular formula C17H8Cl2F3N5 and a molecular weight of 410.18 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H8Cl2F3N5 |
| Molecular Weight | 410.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
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Recommended Standards
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- SE-(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl) O,O-dihydrogen phosphoroselenoate (CAS 64265-97-0)
- 4-(Chloromethyl)-5-hydroxy-7-methyl-2H-chromen-2-one (CAS 879927-52-3)
- 4-chloro-5-nitro-1,3-dihydropyrrolo[2,3-b]pyridin-2-one (CAS 2306263-86-3)
- Sappanone A (CAS 102067-84-5)
- (1-Methyl-1H-pyrrolo[2,3-b]pyridin-2-yl)boronic acid (CAS 1445801-58-0)
- 5-(4-Methylphenyl)-4-phenyl-4h-1,2,4-triazole-3-thiol (CAS 93378-56-4)
- Methyl 2-bromo-4-cyclopropylbenzoate (CAS 1563534-75-7)
- 2,4,6-Trimethylpyridin-3-amine hydrochloride (CAS 71595-27-2)
- (2S,3S)-2-phenyltetrahydrofuran-3-carboxylic acid (CAS 1820575-08-3)
- Ammonium tetrachloroaurate hydrate (CAS 13874-04-9)
- [Tyr0] Fibrinopeptide A, human (CAS 103226-11-5)
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