Metformin Impurity 12 CAS 32151-75-0
| CAS No. | 32151-75-0 |
| Molecular Formula | C6H12N12 |
| Molecular Weight | 252.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Metformin Impurity 12 is closely related to a nitrile group, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Metformin Impurity 12 (CAS 32151-75-0, C6H12N12) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrile group, an aromatic ring system, Metformin Impurity 12 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 252.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Metformin Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H12N12 |
| Molecular Weight | 252.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Nitrogen Atoms | 12 |
Related Metformin Standards
- Metformin Impurity 15 (CAS 786681-13-8)
- Metformin Impurity 23 (CAS 26690-75-5)
- Metformin Impurity 536 (CAS CATO-C4X-1220536)
- Metformin EP Impurity B (CAS 4405-08-7)
- Metformin impurity 53 (CAS CATO-C4X-122053)
- Metformin EP Impurity C (CAS 1985-46-2)
- Metformin Impurity 538 (CAS CATO-C4X-1220538)
- Metformin Impurity 26 (CAS 32161-06-1)
Recommended Standards
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- Trifluoro-methanesulfonic acid triethynylsilyl ester (CAS 2231141-11-8)
- Oseltamivir Impurity 160 (CAS CATO-C4X-1720160)
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- 3-(2-Chlorophenyl)-cyclohexanone (CAS 141632-22-6)
- 1,2-Dimethylquinolin-4(1H)-one (CAS 6760-40-3)
- 1-(2,6-Dichloro-3-(difluoromethoxy)phenyl)propan-1-one (CAS 1805125-96-5)
- 5-(4-Amino-1-(2,2-diethoxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine (CAS 2001571-40-8)
- 4-(Trifluoromethyl)benzo[b]thiophene-2-carboxamide (CAS 2377846-68-7)
- 4-Methyl-2H-indazole-5-carbonitrile (CAS 478837-29-5)
- Semaglutide Impurity 162 (x TFA Salt) (CAS CATO-C4X-2226162)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com