Metformin EP Impurity B CAS 4405-08-7

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.4405-08-7
Molecular FormulaC4H8N8
Molecular Weight168.16 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Metformin EP Impurity B CAS 4405-08-7 chemical structure

Description

As a certified reference material (CRM), Metformin EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Metformin EP Impurity B (CAS 4405-08-7) is a certified pharmaceutical impurity reference standard with the molecular formula C4H8N8 and a molecular weight of 168.16 g/mol.

Owing to a nitrile group, Metformin EP Impurity B is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 168.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

Physical & Chemical Properties

Molecular FormulaC4H8N8
Molecular Weight168.16 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1958
Nitrogen Atoms8

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