5-Chloro-N-(2,5-dimethoxyphenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide CAS 321533-85-1
| CAS No. | 321533-85-1 |
| Molecular Formula | C14H13ClF3N3O3 |
| Molecular Weight | 363.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 5-Chloro-N-(2,5-dimethoxyphenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide (C14H13ClF3N3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 363.72 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
5-Chloro-N-(2,5-dimethoxyphenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 321533-85-1), molecular formula C14H13ClF3N3O3 and molecular weight 363.72 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-Chloro-N-(2,5-dimethoxyphenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H13ClF3N3O3 |
| Molecular Weight | 363.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 2-(2-Chloro-5-(5-(difluoromethoxy)-1-methyl-1H-pyrazol-3-yl)-4-fluorophenoxy)-N-methylacetamide (CAS 2151827-00-6)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(prop-2-yn-1-yl)-1H-pyrrole-2-sulfonamide (CAS 338407-37-7)
- 5-(3-Chloro-4-methoxyphenyl)-N-(2,4-difluorophenyl)furan-2-carboxamide (CAS 853333-72-9)
- 3-(2-Chloro-6-fluorobenzyl)-1-((6-fluoropyridin-2-yl)amino)-4-hydroxypyridin-2(1H)-one (CAS 400077-42-1)
- 6-Chloro-N4-(3,4-dichlorobenzyl)-N2-methyl-5-(methylthio)pyrimidine-2,4-diamine (CAS 400074-35-3)
- N-(2-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclohexanecarboxamide (CAS 2246655-25-2)
- (1E)-1-(5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)-N-[3-(trifluoromethyl)phenyl]methanimine (CAS 320422-71-7)
- 8-Chloro-2-((2R,4S)-2-(2,5-difluorophenyl)-4-fluoropyrrolidin-1-yl)-1,5-naphthyridine (CAS 2419129-92-1)
Recommended Standards
- Elexacaftor Impurity 2 (CAS 2229861-17-8)
- 2-(4-Chlorophenyl)-2-oxoethyl 2-methyl-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate (CAS 339026-40-3)
- (E)-2-(ethylthio)-1-methyl-5-((2-(2,4,6-trichlorophenyl)hydrazono)methyl)-1H-imidazole (CAS 477845-49-1)
- tert-Butyl (3-chloro-4,5-bis(trifluoromethyl)phenyl)carbamate (CAS 2803283-48-7)
- 2-Methyl-4-[(4-trifluoromethyl)phenyl]-1-butene (CAS 113947-86-7)
- 4-Methoxy-3-methylpicolinonitrile (CAS 886372-21-0)
- Ethyl 1-(6-chloropyridin-2-yl)piperidine-4-carboxylate (CAS 1158984-51-0)
- Sodium 4-Hydroxynaphthalene-2-sulfonate (CAS 13935-00-7)
- Ritonavir EP Impurity A (CAS 154212-61-0)
- 3-(5-(tert-Butyl)-2-methylphenyl)propanal (CAS 173445-62-0)
- 3-CHLORO-5-(DIFLUOROMETHYL)PICOLINALDEHYDE (CAS 1803703-03-8)
- Mavacoxib Impurity 9 (CAS CATO-C4X-30599)
- tert-Butyl (3aS,7aR)-rel-octahydro-1H-pyrrolo[3,2-c]pyridine-5-carboxylate (CAS 1250993-54-4)
- Protein Kinase C (alpha) Peptide (CAS 159939-84-1)
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