2-Chloro-5-(methylsulfonyl)pyrimidine CAS 321565-33-7
| CAS No. | 321565-33-7 |
| Molecular Formula | C5H5ClN2O2S |
| Molecular Weight | 192.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Chloro-5-(methylsulfonyl)pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-Chloro-5-(methylsulfonyl)pyrimidine (CAS 321565-33-7) is a high-purity analytical reference standard with the molecular formula C5H5ClN2O2S and a molecular weight of 192.62 g/mol.
2-Chloro-5-(methylsulfonyl)pyrimidine (C5H5ClN2O2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H5ClN2O2S |
| Molecular Weight | 192.62 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- ethyl 4-chloro-1,2,5-thiadiazole-3-carboxylate (CAS 1048982-04-2)
- 4-chloro-5-fluoro-1H,2H,3H-pyrrolo[2,3-b]pyridin-2-one (CAS 1190315-74-2)
- 2-Chloro-3-(methylsulfonyl)pyrazine (CAS 1209459-15-3)
- 2-Chloro-4-(methylsulfonyl)pyrimidine (CAS 1233026-31-7)
- 5-Chloro-4-methoxythiophene-3-carboxylic acid (CAS 133659-14-0)
- Ethyl 5-chloro-1,2,4-thiadiazole-3-carboxylate (CAS 1346147-95-2)
- 4-Chloro-3-methoxythiophene-2-carboxylic acid (CAS 1508708-17-5)
- 2-chloro-1-[1-(fluoromethyl)-2-oxabicyclo[2.1.1]hexan-4-yl]ethanone (CAS 2573212-76-5)
Recommended Standards
- 2-Chlorobenzenesulfonic acid (CAS 27886-58-4)
- 5-Chloropyridine-2-sulfonamide (CAS 19506-41-3)
- 2-Chloro-N-(4-oxo-4,5-dihydrothiazol-2-yl)acetamide (CAS 340266-01-5)
- 2-Aminopyridine-4-sulfonyl chloride (CAS 1890794-11-2)
- N-Boc-3-(bromomethyl)aniline (CAS 118684-32-5)
- 3-(5,6-Dimethyl-1-propyl-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one (CAS 860787-77-5)
- 2-Ammonio-4-methylpentyl sulfate (CAS 1417738-30-7)
- 5-Chloro-2-phenylimidazo[1,2-a]pyridine (CAS 959290-56-3)
- 4-chloro-3,5-difluoropyridine-2-carbaldehyde (CAS 1350648-44-0)
- 2-(2,5-dimethylphenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one (CAS 733795-38-5)
- Methyl 2-(1-methyl-4-nitro-1H-pyrazol-5-yl)acetate (CAS 1586043-71-1)
- 2-Bromo-3-chlorohexafluoro-2-butene (CAS 122557-08-8)
- 4-Aminothiane-4-carboxylic acid hydrochloride (CAS 67639-41-2)
- Cholecystokinin Octapeptide (sulfated) (H-2060.0005) (CAS 25679-23-6)
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