N-(2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2-methylhydrazine-1-carbonyl)-1,3-dimethyl-1H-pyrazole-4-carboxamide CAS 321574-36-1
| CAS No. | 321574-36-1 |
| Molecular Formula | C14H14ClF3N6O2 |
| Molecular Weight | 390.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, N-(2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2-methylhydrazine-1-carbonyl)-1,3-dimethyl-1H-pyrazole-4-carboxamide (C14H14ClF3N6O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 390.75 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
N-(2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2-methylhydrazine-1-carbonyl)-1,3-dimethyl-1H-pyrazole-4-carboxamide (CAS 321574-36-1) is a high-purity analytical reference standard with the molecular formula C14H14ClF3N6O2 and a molecular weight of 390.75 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H14ClF3N6O2 |
| Molecular Weight | 390.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 6 |
Related N Standards
- 3-(2-Chloro-6-fluorobenzyl)-4-hydroxy-1-((3-nitropyridin-2-yl)amino)pyridin-2(1H)-one (CAS 338393-87-6)
- N-(3-Chloro-4-fluorophenyl)-N-(7-methoxy-6-nitroquinazolin-4-yl)acetamide (CAS 869199-61-1)
- 3-chloro-2-{5-[2-(1H-imidazol-1-yl)phenyl]-1H-1,2,4-triazol-1-yl}-5-(trifluoromethyl)pyridine 338793-55-8 KS-00003AZB (CAS 338793-55-8)
- 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)(cyano)methyl)phenyl methanesulfonate (CAS 338410-42-7)
- N-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-2-((methylsulfonamido)oxy)acetamide (CAS 303151-75-9)
- 2-((2-chloro-4-(cyclopropylamino)pyrimidine-5-carbonyl)oxy)-4-(cyclopropylamino)pyrimidine-5-carboxylic acid (CAS CATO-C3D-262479)
- N-(4-Chloro-phenyl)-4-(6-methyl-4-trifluoromethyl-pyridin-2-yl)-benzamide (CAS 1311278-25-7)
- N-(4-Chloro-phenyl)-3-(6-methyl-4-trifluoromethyl-pyridin-2-yl)-benzamide (CAS 1311279-96-5)
Recommended Standards
- 2-[(4-Chlorophenyl)amino]-6-oxo-4-[4-(trifluoromethyl)phenyl]-1,6-dihydropyrimidine-5-carbonitrile (CAS 1349445-93-7)
- Brexpiprazole impurity 105 (CAS CATO-C4X-1131105)
- 1-(4-Chlorobenzyl)-3-(3-fluorophenyl)-1-(3,3,3-trifluoro-2-hydroxypropyl)urea (CAS 478258-84-3)
- Brexpiprazole Impurity 100 (CAS CATO-C4X-1131100)
- Ammethyl-3-phenoxybenzeneacetaldehyde (CAS 59908-87-1)
- 4-sec-Butylbenzenesulfonyl Chloride (CAS 56609-83-7)
- 1-(3,4-Dichlorophenyl)-N-(2-methoxyethyl)methanesulfonamide (CAS 1280835-56-4)
- Calcium sulfate dihydrate (CAS 10101-41-4)
- 5-Methyl-1,2,4-triazin-3-amine (CAS 6302-68-7)
- Deoxycholic acid Impurity 42 (CAS CATO-C4X-335942)
- Arginine Impurity 17 (CAS 151512-14-0)
- (E)-2-Methyl-4-(2,6,6-trimethylcyclohex-2-en-1-yl)but-3-enal (CAS 68555-62-4)
- Dimethyl 1-(p-tolyl)-1H-1,2,3-triazole-4,5-dicarboxylate (CAS 166031-15-8)
- Vasonatrin Peptide (VNP) trifluoroacetate salt (CAS 141676-35-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com