6-(5-Chlorothiophen-2-yl)nicotinaldehyde CAS 323595-47-7
| CAS No. | 323595-47-7 |
| Molecular Formula | C10H6ClNOS |
| Molecular Weight | 223.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
6-(5-Chlorothiophen-2-yl)nicotinaldehyde (CAS 323595-47-7) is a high-purity analytical reference standard with the molecular formula C10H6ClNOS and a molecular weight of 223.68 g/mol.
Structurally, 6-(5-Chlorothiophen-2-yl)nicotinaldehyde (C10H6ClNOS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 223.68 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H6ClNOS |
| Molecular Weight | 223.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chlorothiophen Standards
- (5-Chlorothiophen-2-yl)(pyridin-2-yl)methanone (CAS 515154-33-3)
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- 2-{[(5-chlorothiophen-2-yl)methyl]sulfanyl}acetic acid (CAS 178974-87-3)
- (5-Chlorothiophen-2-yl)(phenyl)methanone (CAS 56824-84-1)
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- 4-(3-Chlorothiophen-2-yl)-6-methylpyrimidin-2-amine (CAS 863305-81-1)
- 4-(5-Chlorothiophen-2-yl)-6-methylpyrimidin-2-amine (CAS 199864-44-3)
- 3-(5-Chlorothiophen-2-yl)-5,6-dihydro-4H-pyrrolo[3,2-d]isoxazole (CAS 603068-05-9)
Recommended Standards
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- 5-(chloromethyl)-N,N-dimethylfuran-2-sulfonamide (CAS 56038-68-7)
- 6752-38-1 AR-1J8860 n-(4-{bis[4-(dimethylamino)phenyl]methylidene}cyclohexa-2,5-dien-1-ylidene)-n-methylmethanaminium zinc chloride(2:1:4) (CAS 6752-38-1)
- Nα-Tosyl-Lys Chloromethyl Ketone, Hydrochloride (CAS 4238-41-9)
- (S)-1-(2-Aminoethyl)-3-methoxypyrrolidin-2-one (CAS 2377183-12-3)
- Ethyl 1-(4-fluorophenyl)-1H-1,2,4-triazole-3-carboxylate (CAS 1613022-95-9)
- (3-Cyano-2-iodophenyl)boronic acid (CAS 1257793-11-5)
- Methyl 5-acetyl-1,2,4-trimethyl-1H-pyrrole-3-carboxylate (CAS 90433-82-2)
- 2-Acetoxysuccinic acid (CAS 52485-05-9)
- N-((2-Chloro-5-(N-(3-chlorophenyl)sulfamoyl)phenyl)carbamothioyl)-4-fluorobenzamide (CAS 379712-59-1)
- 2-Bromo-3-bromomethyl-6-(trifluoromethyl)pyridine (CAS 888738-20-3)
- 2-(2,6-Dimethoxy-4-methylphenoxy)acetic acid (CAS 857555-80-7)
- Semaglutide impurity 62 (CAS CATO-C4X-222662)
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