5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-2-methyl-3-phenyl-hexahydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione CAS 324009-27-0
| CAS No. | 324009-27-0 |
| Molecular Formula | C19H16ClF3N4O3 |
| Molecular Weight | 440.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-2-methyl-3-phenyl-hexahydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione (CAS 324009-27-0), molecular formula C19H16ClF3N4O3 and molecular weight 440.80 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-2-methyl-3-phenyl-hexahydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione (C19H16ClF3N4O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-2-methyl-3-phenyl-hexahydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H16ClF3N4O3 |
| Molecular Weight | 440.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related chloro Standards
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Recommended Standards
- ((1,3,5-Triazine-2,4,6-triyl)tris(benzene-4,1-diyl))triboronic acid (CAS 910231-21-9)
- 17a(H),21B(H)-(22RS)-Bishomohopane (CAS 54352-50-0)
- (R)-2,2,2-Trichloroethyl 4-(3-amino-4-(phenylthio)butyl)piperazine-1-carboxylate (CAS 2143096-87-9)
- 17a(H),21a(H)-(22RS)-Bishomohopane (CAS 105498-25-7)
- Ethyl 4-bromo-7-chloro-6-methoxyquinoline-3-carboxylate (CAS 1378259-31-4)
- Benoxacor (CAS 98730-04-2)
- 5-ISOPROPYL-2-METHOXYBENZENE-1-SULFONYL CHLORIDE (CAS 88059-65-8)
- Ethyl 6,7-Dimethoxyquinoline-3-carboxylate (CAS 5278-39-7)
- Ethyl 4-bromo-6-hydroxypicolinate (CAS 1807101-65-0)
- 4-Bromo-2-ethylaniline (CAS 45762-41-2)
- Mepyramine N-Oxide (CAS 98982-99-1)
- 4-Amino-3-iodobenzotrifluoride (CAS 163444-17-5)
- 3-Hydroxy-4-methylbenzohydrazide (CAS 39635-23-9)
- Cholecystokinin Octapeptide (sulfated) (H-2060.0005) (CAS 25679-23-6)
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