2-(Thiophen-2-yl)-1,3-thiazolidine-4-carboxylic acid CAS 32451-19-7
| CAS No. | 32451-19-7 |
| Molecular Formula | C8H9NO2S2 |
| Molecular Weight | 215.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-(Thiophen-2-yl)-1,3-thiazolidine-4-carboxylic acid (CAS 32451-19-7) is a high-purity analytical reference standard with the molecular formula C8H9NO2S2 and a molecular weight of 215.29 g/mol.
The molecular framework of 2-(Thiophen-2-yl)-1,3-thiazolidine-4-carboxylic acid (C8H9NO2S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9NO2S2 |
| Molecular Weight | 215.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Thiophen Standards
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