N-(4-(4-Chlorophenyl)thiazol-2-yl)-5-nitrothiophene-2-carboxamide CAS 324758-78-3
| CAS No. | 324758-78-3 |
| Molecular Formula | C14H8ClN3O3S2 |
| Molecular Weight | 365.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C14H8ClN3O3S2, N-(4-(4-Chlorophenyl)thiazol-2-yl)-5-nitrothiophene-2-carboxamide contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 365.81 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies N-(4-(4-Chlorophenyl)thiazol-2-yl)-5-nitrothiophene-2-carboxamide (CAS 324758-78-3), a certified reference material (molecular formula C14H8ClN3O3S2, MW 365.81 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-(4-(4-Chlorophenyl)thiazol-2-yl)-5-nitrothiophene-2-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8ClN3O3S2 |
| Molecular Weight | 365.81 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related N Standards
- 5-(4-Chlorophenyl)-3-(3,4-dimethoxyphenyl)pyrazolo[1,5-a]pyrimidine (CAS 866144-81-2)
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- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(2,4-difluorophenyl)acetamide (CAS 477320-17-5)
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- 2-(2-((4-Chlorophenyl)sulfonyl)-1,2,3,4-tetrahydroisoquinolin-1-yl)acetic acid (CAS 378227-98-6)
- 2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-(pyridin-4-yl)-1,2-dihydro-3H-pyrazol-3-one (CAS 219138-24-6)
- 5-((4-Chlorophenyl)thio)-N-(4-fluorophenyl)-1,2,3-thiadiazole-4-carboxamide (CAS 338791-89-2)
Recommended Standards
- Methyl 4-(2-Chloro-4-fluorophenyl)-6-methyl-2-(2-thiazolyl)-1,4-dihydropyrimidine-5-carboxylate (CAS 247037-77-0)
- N-(4-(5-Chlorothiophen-2-yl)thiazol-2-yl)-2-nitrobenzamide (CAS 330677-85-5)
- Ethyl (R)-4-(2-Chloro-4-fluorophenyl)-6-methyl-2-(2-thiazolyl)-1,4-dihydropyrimidine-5-carboxylate (CAS 247037-81-6)
- Amlodipine Impurity 53 (CAS CATO-C4X-109553)
- 2-tert-Butyl 3-ethyl (3S)-2,8-diazaspiro[4.5]decane-2,3-dicarboxylate (CAS 1675970-16-7)
- 4-Bromo-2-methylpyrimidine-5-carboxylic acid (CAS 1525149-72-7)
- 3-[(4-Aminophenyl)thio]-1-(4-ethoxyphenyl)pyrrolidine-2,5-dione (CAS 913243-76-2)
- 4-Ethyl-1,2-difluorobenzene (CAS 116850-25-0)
- 1-Methyl-N-(tetrahydrothiophen-3-yl)-1H-pyrazol-4-amine (CAS 1153293-93-6)
- 2-Amino-4-ethyl-5-methyl-N-phenylthiophene-3-carboxamide (CAS 590353-67-6)
- Isomagnolol (CAS 87688-90-2)
- 27856-54-8 Cyclopenta[c]pyran-4-carboxylicacid, 1-(b-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-4a,6,7-trihydroxy-7-methyl-,methyl ester, (1S,4aR,6S,7R,7aS)- (CAS 27856-54-8)
- Benzyl 3-(N,N-dimethylsulfamoyl)azetidine-1-carboxylate (CAS 1333792-90-7)
- Ephrin-A2-Selective YSA-Peptide (CAS 532441-10-4)
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