2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(2,5-difluorophenyl)acetamide CAS 303091-78-3
| CAS No. | 303091-78-3 |
| Molecular Formula | C18H18ClF2N3O |
| Molecular Weight | 365.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(2,5-difluorophenyl)acetamide (CAS 303091-78-3), a certified reference material (molecular formula C18H18ClF2N3O, MW 365.80 g/mol) for analytical method development and quality control.
2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(2,5-difluorophenyl)acetamide (C18H18ClF2N3O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(2,5-difluorophenyl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H18ClF2N3O |
| Molecular Weight | 365.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(2,4-difluorophenyl)acetamide (CAS 477320-17-5)
- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(3,4-difluorophenyl)acetamide (CAS 303091-74-9)
- 2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-(pyridin-4-yl)-1,2-dihydro-3H-pyrazol-3-one (CAS 219138-24-6)
- 5-(4-Chlorophenyl)-3-(3,4-dimethoxyphenyl)pyrazolo[1,5-a]pyrimidine (CAS 866144-81-2)
- N-(3-(4-chlorophenyl)imidazo[1,2-a]pyridin-8-yl)-2-fluorobenzamide (CAS 439096-62-5)
- N-(4-(4-Chlorophenyl)thiazol-2-yl)-5-nitrothiophene-2-carboxamide (CAS 324758-78-3)
- 2-(4-(6-((4-Chlorophenyl)amino)-9H-purin-9-yl)phenyl)ethanol (CAS 16208-00-7)
- 2-(2-((4-Chlorophenyl)sulfonyl)-1,2,3,4-tetrahydroisoquinolin-1-yl)acetic acid (CAS 378227-98-6)
Recommended Standards
- 2,3,5-Tribromo-4-(difluoromethyl)pyridine (CAS 1361880-23-0)
- N-(3-chloro-4-fluorophenyl)-2-(4-(2-fluorophenyl)piperazin-1-yl)acetamide (CAS 329080-46-8)
- Clinafloxacin (CAS 105956-97-6)
- N-(3-chloro-4-fluorophenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)acetamide (CAS 329079-97-2)
- 1-(Aminomethyl)cyclopropanecarboxylic acid (CAS 139126-45-7)
- 3-Heptadecyl-4-methyl-1-phenyl-1H-pyrazol-5(4H)-one (CAS 111989-07-2)
- 8-Fluoroquinoline-4-carbonitrile (CAS 949535-30-2)
- 5-Chloro-2-cyclopropyl-1H-imidazo[4,5-b]pyridine (CAS 146014-81-5)
- Quifenadine Impurity 1 (CAS 60697-89-4)
- 2-(9-Oxoacridin-10(9H)-yl)ethyl methylcarbamate (CAS 393550-63-5)
- 6-(2-Fluorophenyl)-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 924129-81-7)
- tert-Butyl (1R,4R,5R)-5-amino-2-azabicyclo[2.2.1]heptane-2-carboxylate (CAS 1400808-02-7)
- Ivabradine Impurity 44 (CAS 866783-13-3)
- Glucagon Monohydrochloride (CAS 28270-04-4)
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