6-(Trifluoromethyl)quinoline CAS 325-13-3
| CAS No. | 325-13-3 |
| Molecular Formula | C10H6F3N |
| Molecular Weight | 197.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 6-(Trifluoromethyl)quinoline (CAS 325-13-3), a certified reference material (molecular formula C10H6F3N, MW 197.16 g/mol) for analytical method development and quality control.
6-(Trifluoromethyl)quinoline (C10H6F3N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 6-(Trifluoromethyl)quinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H6F3N |
| Molecular Weight | 197.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 6-(Trifluoromethyl)piperidine-3-carboxylic acid (CAS 1155103-14-2)
- Methyl 4-(trifluoromethyl)pyrrolidine-3-carboxylate (CAS 1190043-09-4)
- 7-(Trifluoromethyl)isoquinoline (CAS 1194375-56-8)
- 6-(Trifluoromethyl)isoquinoline (CAS 1194375-62-6)
- 4-(Trifluoromethyl)isoquinoline (CAS 120568-08-3)
- 8-(trifluoromethyl)isoquinoline (CAS 120568-10-7)
- 2-(Trifluoromethyl)piperidine-3-carboxylic acid (CAS 1240528-93-1)
- 2-(5-(Trifluoromethyl)pyrrolidin-2-yl)acetic acid (CAS 1258640-31-1)
Recommended Standards
- 5-Fluoro-6-(hydroxymethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 2883020-28-6)
- 6-Fluoro-4-nitro-2,3-dihydro-1H-inden-5-ol (CAS 2676865-58-8)
- 5-Acetamido-2-fluorobenzoic acid (CAS 939909-22-5)
- 6-Fluoro-8-nitrochroman (CAS 282547-27-7)
- 2,2'-((2-(1H-Imidazol-4-yl)ethyl)azanediyl)diacetic acid (CAS 744190-30-5)
- N-((S)-((R)-5-Oxo-2,5-dihydrofuran-2-yl)(phenyl)methyl)acetamide (CAS 919770-48-2)
- Ethyl 2-(3,4-dimethyl-6-oxo-2,6-dihydropyrano[2,3-c]pyrazol-5-yl)acetate (CAS 439121-65-0)
- 4,4,4-Trifluoro-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butan-1-amine (CAS 319009-82-0)
- 1-(Phenylsulfonyl)piperidin-4-one O-(3-chlorobenzoyl) oxime (CAS 477847-27-1)
- 2,4-Bis(trifluoromethyl)-6-methoxybenzyl alcohol (CAS 1805405-28-0)
- 1-(4-((8-Chloroquinolin-4-yl)amino)phenyl)ethan-1-one (CAS 955328-58-2)
- N,N-Dimethyl-2-[[2-Phenyl-8-(Trifluoromethyl)-4-Quinazolinyl]Thio]-Acetamide (CAS 606131-37-7)
- 4-Phenylthiophene-2-carbaldehyde (CAS 26170-87-6)
- Peptide Impurity 11 X TFA Salt (CAS CATO-CPTD788811)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com