1-[2-nitro-4-(trifluoromethyl)phenyl]piperidine-4-carboxylic acid CAS 325702-10-1

Purity 97%+In StockPharmaceutical Standards
CAS No.325702-10-1
Molecular FormulaC13H13F3N2O4
Molecular Weight318.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-[2-nitro-4-(trifluoromethyl)phenyl]piperidine-4-carboxylic acid CAS 325702-10-1 chemical structure

Description

1-[2-nitro-4-(trifluoromethyl)phenyl]piperidine-4-carboxylic acid (C13H13F3N2O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

1-[2-nitro-4-(trifluoromethyl)phenyl]piperidine-4-carboxylic acid (CAS 325702-10-1), molecular formula C13H13F3N2O4 and molecular weight 318.25 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 1-[2-nitro-4-(trifluoromethyl)phenyl]piperidine-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC13H13F3N2O4
Molecular Weight318.25 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms2

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