1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-3-(4-(dimethylamino)phenyl)thiourea CAS 326815-26-3
| CAS No. | 326815-26-3 |
| Molecular Formula | C16H16ClF3N4S |
| Molecular Weight | 388.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-3-(4-(dimethylamino)phenyl)thiourea is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-3-(4-(dimethylamino)phenyl)thiourea (CAS 326815-26-3), a certified reference material (molecular formula C16H16ClF3N4S, MW 388.84 g/mol) for analytical method development and quality control.
The molecular framework of 1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-3-(4-(dimethylamino)phenyl)thiourea (C16H16ClF3N4S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-3-(4-(dimethylamino)phenyl)thiourea under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H16ClF3N4S |
| Molecular Weight | 388.84 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 1-chloro-3,5-ditoluyl-D-deoxyribose (CAS 3601-89-6)
- 2-Chloro-3-(4-(morpholine-4-carbonyl)piperidin-1-yl)naphthalene-1,4-dione (CAS 439108-66-4)
- 2-((2-Chloro-6-fluorobenzyl)thio)-7-(4-fluorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 338417-71-3)
- 2-(N-(5-Chloro-2-methylphenyl)methylsulfonamido)-N-(2,6-difluorophenyl)acetamide (CAS 708219-39-0)
- 3-((5-(5-Chloro-2-hydroxybenzylidene)-3-methyl-4-oxothiazolidin-2-ylidene)amino)benzoic acid (CAS 491582-40-2)
- N-(3-chloro-2-methylphenyl)-3-(2-nitrophenoxy)thiophene-2-carboxamide (CAS 252027-04-6)
- 4-Chloro-5,6-dimethyl-2-(((3-(trifluoromethyl)phenyl)thio)methyl)thieno[2,3-d]pyrimidine (CAS 885460-30-0)
- N-(4-Chloro-2-methylphenyl)-2-((4-ethyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 618427-50-2)
Recommended Standards
- (E)-{1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethylidene}amino 4-fluorobenzoate (CAS 477872-46-1)
- (3E)-1-[2-(4-Chlorophenyl)-1,3-thiazol-5-yl]-3-{[(2-fluorophenyl)methoxy]imino}propan-1-one (CAS 339279-42-4)
- (2R,3S,5R)-5-Chloro-2-[[(4-methylbenzoyl)oxy]methyl]tetrahydrofuran-3-yl 4-Methylbenzoate (CAS 4330-21-6)
- 3-Oxo-3-(2-phenyl-1,3-thiazol-5-yl)propanal O-(2-chloro-4-fluorobenzyl)oxime (CAS 338414-43-0)
- [4-(4-Aminophenoxy)phenyl]boronic acid (CAS 1029438-85-4)
- 5-(Bromomethyl)-2-chloro-3-methylpyridine (CAS 1003859-10-6)
- (2-(2,4,5-Trimethoxyphenyl)cyclopropyl)methanamine (CAS 1272883-89-2)
- 5-Chloro-3-fluoro-pyridine-2-carboxylic acid amide (CAS 207994-10-3)
- 7,7-Dimethyl-1-azaspiro[3.5]nonan-2-one (CAS 178243-37-3)
- 4-Phenyl-2H-benzo[4,5]thiazolo[3,2-a]pyrimidin-2-one (CAS 32278-47-0)
- 3,6-Diethylpyrazin-2-ol (CAS 72876-11-0)
- 2-Methylisoindolin-5-amine dihydrochloride (CAS 943751-30-2)
- Bis(prop-2-yn-1-yl)amine hydrochloride (CAS 93282-90-7)
- D-[Phe]6-Liraglutide (CAS CATO-C4X-199235)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com