4-Iodo-N-((tetrahydrofuran-2-yl)methyl)benzenesulfonamide CAS 326885-27-2

Purity 97%+In StockPharmaceutical Standards
CAS No.326885-27-2
Molecular FormulaC11H14INO3S
Molecular Weight367.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Iodo-N-((tetrahydrofuran-2-yl)methyl)benzenesulfonamide CAS 326885-27-2 chemical structure

Description

The occurrence of 4-Iodo-N-((tetrahydrofuran-2-yl)methyl)benzenesulfonamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-Iodo-N-((tetrahydrofuran-2-yl)methyl)benzenesulfonamide (CAS 326885-27-2) is a high-purity analytical reference standard with the molecular formula C11H14INO3S and a molecular weight of 367.20 g/mol.

The molecular framework of 4-Iodo-N-((tetrahydrofuran-2-yl)methyl)benzenesulfonamide (C11H14INO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H14INO3S
Molecular Weight367.20 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentI-containing
Nitrogen Atoms1
Sulfur Atoms1

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