4-(4-Bromophenyl)-6-(trifluoromethyl)pyrimidin-2-amine CAS 327098-68-0
| CAS No. | 327098-68-0 |
| Molecular Formula | C11H7BrF3N3 |
| Molecular Weight | 318.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(4-Bromophenyl)-6-(trifluoromethyl)pyrimidin-2-amine.
4-(4-Bromophenyl)-6-(trifluoromethyl)pyrimidin-2-amine (CAS 327098-68-0) is a high-purity analytical reference standard with the molecular formula C11H7BrF3N3 and a molecular weight of 318.09 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution, 4-(4-Bromophenyl)-6-(trifluoromethyl)pyrimidin-2-amine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 318.09 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(4-Bromophenyl)-6-(trifluoromethyl)pyrimidin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H7BrF3N3 |
| Molecular Weight | 318.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 3 |
Related Bromophenyl Standards
- 1-(1-(4-Bromophenyl)-1H-pyrrol-2-yl)-2,2,2-trifluoroethan-1-one (CAS 477848-98-9)
- 3-(5-(2-Bromophenyl)furan-2-yl)-2-cyanoacrylic acid (CAS 853347-63-4)
- 2-(4-Bromophenyl)-6-nitroimidazo[1,2-a]pyridine (CAS 118000-56-9)
- 3-[3-(4-Bromophenyl)-1,2,4-oxadiazol-5-yl]-1,2-dihydropyridin-2-one (CAS 1223888-66-1)
- (2Z)-3-[3-(2-bromophenyl)-1H-pyrazol-4-yl]-2-cyanoacrylic acid (CAS 926190-05-8)
- 1-(4-Bromophenyl)-5-nitro-1H-benzo[d]imidazole (CAS 7104-54-3)
- 2-(4-Bromophenyl)-8-nitroimidazo[1,2-a]pyridine (CAS 866051-28-7)
- 3-[3-(3-bromophenyl)-1h-pyrazol-4-yl]-2-cyanoprop-2-enoic acid (CAS 926240-84-8)
Recommended Standards
- 1,1,2,2-Tetrafluoro-2-(perfluoroethoxy)ethane-1-sulfonyl fluoride (CAS 67990-78-7)
- 5-bromo-N-[3-(trifluoromethyl)phenyl]pyrimidin-2-amine (CAS 956127-82-5)
- 2-(4-Methoxy-3-(trifluoromethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1005009-96-0)
- 2-Bromo-6-(3-(trifluoromethoxy)phenyl)pyridine (CAS 1482180-88-0)
- Propan-2-ylidenehydrazine (CAS 5281-20-9)
- 4-(2-Chloroacetamido)butanoic acid (CAS 649556-05-8)
- 1-(2,4,6-Trihydroxyphenyl)hexan-1-one, 97% (CAS 5665-89-4)
- N-Methyl-1-(2-methyl-5-pyrimidyl)methylamine (CAS 1248406-79-2)
- 3-(Ethylsulfonyl)pyrazolo[1,5-a]pyrimidin-6-amine (CAS 1708260-79-0)
- Di-tert-butyl 2-methylmalonate (CAS 34812-95-8)
- Ethyl ((4-(trifluoromethyl)phenyl)carbamothioyl)glycinate (CAS 321433-99-2)
- N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-(1H-indol-3-yl)propanamide (CAS 742116-45-6)
- Vonoprazan Impurity 253 (CAS CATO-C4X-1020253)
- Des-Ser34-Gly33Tirzepatide (CAS CATO-CPTD788941)
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