Vonoprazan Impurity 253 CAS CATO-C4X-1020253
| CAS No. | CATO-C4X-1020253 |
| Molecular Formula | C22H17Cl2F2N3 |
| Molecular Weight | 432.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Vonoprazan Impurity 253 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Vonoprazan Impurity 253 (CAS CATO-C4X-1020253) is a certified pharmaceutical impurity reference standard with the molecular formula C22H17Cl2F2N3 and a molecular weight of 432.29 g/mol.
Vonoprazan Impurity 253 (C22H17Cl2F2N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C22H17Cl2F2N3 |
| Molecular Weight | 432.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Vonoprazan Standards
- Vonoprazan Fumarate Impurity 122 (CAS CATO-C4X-1020122)
- Vonoprazan Impurity 296 (CAS CATO-C4X-1020296)
- Vonoprazan Impurity 185 (CAS CATO-C4X-1020185)
- Vonoprazan Impurity 174 (CAS CATO-C4X-1020174)
- Vonoprazan Impurity 238 (CAS 1831110-76-9)
- Vonoprazan Impurity 145 (CAS CATO-C4X-1020145)
- Vonoprazan Impurity 66 (CAS 2170020-79-6)
- Vonoprazan Impurity 256 (CAS CATO-C4X-1020256)
Recommended Standards
- PU-H58 (CAS 852030-47-8)
- Methyl 2-[bis({6-chloroimidazo[1,2-a]pyridin-3-yl}methyl)amino]propanoate (CAS 1025762-32-6)
- N'-[5,7-Bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-4-fluoro-N'-methylbenzohydrazide (CAS 320417-56-9)
- [cyano-[3-(4-hydroxyphenoxy)phenyl]methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate (CAS 64691-63-0)
- Iguratimod Impurity 28 HCl (CAS CATO-C4X-182628)
- Etoricoxib Impurity 76 (CAS CATO-C4X-108076)
- Guaiacol EP Impurity F (CAS 2896-67-5)
- 1-[3,5-DImethyl-1-(2-methylphenyl)-1h-pyrazol-4-yl]methanamine dihydrochloride (CAS 2108832-00-2)
- Benfotiamine Impurity 3 (CAS CATO-C4X-28163)
- Brinzolamide Impurity 23 (CAS 138890-58-1)
- N-((2S,3R,4R,5S,6R)-2-((6-chloro-1H-indol-3-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide (CAS 156117-44-1)
- Dihydrogenistein (CAS 21554-71-2)
- Tert-butyl (R)-(2-(hydroxymethyl)pentyl)carbamate (CAS 896721-68-9)
- Semaglutide impurity 70 (CAS CATO-C4X-222670)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com