Isoflurane EP Impurity D CAS 32778-07-7
| CAS No. | 32778-07-7 |
| Molecular Formula | C3HCl2F5O |
| Molecular Weight | 218.94 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 218.94 g/mol gives Isoflurane EP Impurity D distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Isoflurane EP Impurity D (CAS 32778-07-7) is a certified pharmaceutical impurity reference standard with the molecular formula C3HCl2F5O and a molecular weight of 218.94 g/mol.
The molecular framework of Isoflurane EP Impurity D (C3HCl2F5O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Isoflurane EP Impurity D meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C3HCl2F5O |
| Molecular Weight | 218.94 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | F/Cl-containing |
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