N-(5-chloropyridin-2-yl)-4-fluorobenzamide CAS 327991-18-4

Purity 97%+In StockPharmaceutical Standards
CAS No.327991-18-4
Molecular FormulaC12H8ClFN2O
Molecular Weight250.66 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(5-chloropyridin-2-yl)-4-fluorobenzamide CAS 327991-18-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 250.66 g/mol gives N-(5-chloropyridin-2-yl)-4-fluorobenzamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies N-(5-chloropyridin-2-yl)-4-fluorobenzamide (CAS 327991-18-4), a certified reference material (molecular formula C12H8ClFN2O, MW 250.66 g/mol) for analytical method development and quality control.

The molecular framework of N-(5-chloropyridin-2-yl)-4-fluorobenzamide (C12H8ClFN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures N-(5-chloropyridin-2-yl)-4-fluorobenzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H8ClFN2O
Molecular Weight250.66 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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