N-(2-Chloro-6-nitrophenyl)methanesulfonamide CAS 2140305-58-2
| CAS No. | 2140305-58-2 |
| Molecular Formula | C7H7ClN2O4S |
| Molecular Weight | 250.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies N-(2-Chloro-6-nitrophenyl)methanesulfonamide (CAS 2140305-58-2), a certified reference material (molecular formula C7H7ClN2O4S, MW 250.66 g/mol) for analytical method development and quality control.
Structurally, N-(2-Chloro-6-nitrophenyl)methanesulfonamide (C7H7ClN2O4S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 250.66 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H7ClN2O4S |
| Molecular Weight | 250.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related N Standards
- 2-Chloro-N-(3-fluorophenyl)isonicotinamide (CAS 1019323-09-1)
- 2-Chloro-N-(4-fluorophenyl)isonicotinamide (CAS 1019383-51-7)
- 2-Chloro-N-(2-fluorophenyl)isonicotinamide (CAS 1019466-42-2)
- Methyl 2-Chloro-5-sulfamoylnicotinate (CAS 1118787-24-8)
- 5-(3-Chloro-2-fluorophenyl)nicotinamide (CAS 1125445-55-7)
- n-(4-Chloro-2-nitrophenyl)methanesulfonamide (CAS 1249400-38-1)
- n-(2-Chloro-6-nitrophenyl)methanesulfonamide (CAS 1339907-56-0)
- 5-(4-Chloro-2-fluorophenyl)nicotinamide (CAS 1346691-88-0)
Recommended Standards
- Methyl 6-chloro-2-(methylsulfonyl)pyrimidine-4-carboxylate (CAS 25742-28-3)
- N-(5-chloropyridin-2-yl)-2-fluorobenzamide (CAS 34556-81-5)
- Methyl 5-chloro-2-(methylsulfonyl)pyrimidine-4-carboxylate (CAS 79685-41-9)
- N-(5-chloropyridin-2-yl)-4-fluorobenzamide (CAS 327991-18-4)
- 6-Bromo-N-(piperidin-3-ylmethyl)pyridin-2-amine hydrochloride (CAS 1185310-62-6)
- 1-[4-(Trifluoromethyl)phenyl]cyclobutanamine (CAS 1270577-37-1)
- 5-(6-Fluoro-2,3-dimethoxyphenyl)oxazole (CAS 2379322-64-0)
- N-[(4Z)-3-Ethyl-2-oxo-1,2,3,4-tetrahydroquinazolin-4-ylidene]-4-methylbenzamide (CAS 478032-91-6)
- Ibrutinib Impurity 113 (CAS CATO-C4X-1064113)
- 2-Amino-3-(4-methoxy-3-nitrophenyl)propanoic acid (CAS 90899-87-9)
- (4-(1-Aminoethyl)piperidin-1-yl)(cyclopropyl)methanone (CAS 1340534-99-7)
- 2-(4-Chlorophenyl)-1-(piperazin-1-yl)ethan-1-one (CAS 926187-94-2)
- 5-(2-Chlorophenyl)-1,3,4-oxadiazole-2-thiol (CAS 23766-27-0)
- Semaglutide impurity 290 (CAS CATO-C4X-2226290)
Why CATO?
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