3-Bromo-5-(trifluoromethyl)benzoic Acid CAS 328-67-6
| CAS No. | 328-67-6 |
| Molecular Formula | C8H4BrF3O2 |
| Molecular Weight | 269.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-Bromo-5-(trifluoromethyl)benzoic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 3-Bromo-5-(trifluoromethyl)benzoic Acid (CAS 328-67-6), a certified reference material (molecular formula C8H4BrF3O2, MW 269.02 g/mol) for analytical method development and quality control.
Structurally, 3-Bromo-5-(trifluoromethyl)benzoic Acid (C8H4BrF3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 269.02 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H4BrF3O2 |
| Molecular Weight | 269.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 5-Bromo-2-(trifluoromethyl)isonicotinamide (CAS 1070892-03-3)
- 2-Bromo-4-(trifluoromethoxy)benzaldehyde (CAS 1114808-87-5)
- 2-Bromo-6-(trifluoromethoxy)benzaldehyde (CAS 1114809-17-4)
- 1-(4-Bromo-2-hydroxyphenyl)-2,2,2-trifluoroethan-1-one (CAS 1184850-45-0)
- 1-(5-Bromo-2-hydroxyphenyl)-2,2,2-trifluoroethan-1-one (CAS 1190130-82-5)
- 2-Bromo-6-(trifluoromethyl)nicotinamide (CAS 1214332-09-8)
- 4-Bromo-3-(trifluoromethoxy)benzaldehyde (CAS 1221716-04-6)
- 3-Bromo-2-(trifluoromethyl)benzoic acid (CAS 1227605-02-8)
Recommended Standards
- 3-Bromo-5-(trifluoromethoxy)benzaldehyde (CAS 886498-07-3)
- 3-Bromophenyl trifluoroacetate (CAS 59935-55-6)
- 3-Bromo-4-(trifluoromethyl)benzoic Acid (CAS 581813-17-4)
- 4-Bromo-2-(trifluoromethoxy)benzaldehyde (CAS 220996-80-5)
- 1-Boc-4-(4-amino-3-methoxyphenyl)piperazine (CAS 1246532-96-6)
- 2-(3-Bromo-4-chlorophenyl)propan-2-amine hydrochloride (CAS 1314722-34-3)
- 6-((3-(5-Methyl-1h-pyrazol-4-yl)propyl)amino)nicotinonitrile (CAS 1289614-85-2)
- Platinate(2-), tetrachloro-, rubidium (1:2), (SP-4-1)- (CAS 13820-56-9)
- (R)-1-(2-Morpholinophenyl)ethan-1-amine (CAS 1212879-51-0)
- 3-Fluoro-3-methyl[1,1-biphenyl]-4-amine (CAS 893735-47-2)
- tert-Butyl 4-(4-methylpyrimidin-5-yl)piperazine-1-carboxylate (CAS 1956381-42-2)
- N-(4-(2-Oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)phenyl)-3,3-diphenylpropanamide (CAS 1234809-05-2)
- (1R,2R)-Cyclobutane-1,2-dicarboxylic acid (CAS 17224-72-5)
- Semaglutide impurity 43 (CAS CATO-C4X-222643)
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