2-Chloro-1,4-bis(trifluoromethyl)benzene CAS 328-91-6
| CAS No. | 328-91-6 |
| Molecular Formula | C8H3ClF6 |
| Molecular Weight | 248.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Chloro-1,4-bis(trifluoromethyl)benzene is closely related to fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-Chloro-1,4-bis(trifluoromethyl)benzene (CAS 328-91-6), a certified reference material (molecular formula C8H3ClF6, MW 248.55 g/mol) for analytical method development and quality control.
2-Chloro-1,4-bis(trifluoromethyl)benzene (C8H3ClF6) contains fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Chloro-1,4-bis(trifluoromethyl)benzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H3ClF6 |
| Molecular Weight | 248.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 1-Chloro-2,3-bis(trifluoromethyl)benzene (CAS 1221272-75-8)
- 1-Chloro-3-fluoro-5-(pentafluoroethyl)benzene (CAS 1429056-21-2)
- 2-Chloro-1-fluoro-4-pentafluoroethyl-benzene (CAS 1429056-46-1)
- 2-(1-Chloro-4-methoxybutyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 162854-89-9)
- 4-Chloro-1,2-bis(trifluoromethyl)benzene (CAS 320-30-9)
- 4-chloro-6-(pentafluoroethyl)-1,3,5-triazin-2-amine (CAS 1139245-15-0)
- 5-Chloro-2,2,3,4,4,5,5-heptafluoropentan-1-ol (CAS 261503-63-3)
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Recommended Standards
- 1-(5-Bromo-2-chlorophenyl)-N,N-dimethylmethanamine (CAS 861967-07-9)
- 3,5-Bis(trifluoromethyl)chlorobenzene (CAS 328-72-3)
- [(2-Bromo-6-chlorophenyl)methyl](ethyl)amine (CAS 1862910-15-3)
- 2-Bromo-5-(3-chloropropyl)aniline (CAS 1806433-11-3)
- 2-(5-Chloro-2-oxopyridin-1(2H)-yl)acetonitrile (CAS 124432-35-5)
- (4-(Difluoromethyl)-6-iodopyridin-2-yl)methanol (CAS 1805119-81-6)
- Leupeptin 2,2,2-trifluoroacetate (CAS 147385-61-3)
- 2-(2-(((Benzyloxy)carbonyl)amino)-3-(1H-indol-3-yl)propanamido)-3-(4-hydroxyphenyl)propanoic acid (CAS 20762-34-9)
- 1-(4-fluorophenyl)-3-methyl-1H-pyrazole-4-carbaldehyde (CAS 926190-13-8)
- Sinomenine HCl (CAS 1778681-37-0)
- 3-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-2-sulfanyl-3,4-dihydroquinazolin-4-one (CAS 119426-88-9)
- 2-(2,2,2-Trifluoroacetyl)hydrazinecarbothioamide (CAS 51321-51-8)
- 5-(2-Methoxyethoxy)-1-methyl-1H-pyrazole-3-carboxylic acid (CAS 1707568-61-3)
- Semaglutide impurity 269 (CAS CATO-C4X-2226269)
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