N'-[(1E)-(2-{[(4-chlorophenyl)methyl]sulfanyl}-5-nitrophenyl)methylidene]-2-phenylacetohydrazide CAS 329058-85-7
| CAS No. | 329058-85-7 |
| Molecular Formula | C22H18ClN3O3S |
| Molecular Weight | 439.91 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N'-[(1E)-(2-{[(4-chlorophenyl)methyl]sulfanyl}-5-nitrophenyl)methylidene]-2-phenylacetohydrazide.
CATO supplies N'-[(1E)-(2-{[(4-chlorophenyl)methyl]sulfanyl}-5-nitrophenyl)methylidene]-2-phenylacetohydrazide (CAS 329058-85-7), a certified reference material (molecular formula C22H18ClN3O3S, MW 439.91 g/mol) for analytical method development and quality control.
Structurally, N'-[(1E)-(2-{[(4-chlorophenyl)methyl]sulfanyl}-5-nitrophenyl)methylidene]-2-phenylacetohydrazide (C22H18ClN3O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 439.91 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H18ClN3O3S |
| Molecular Weight | 439.91 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Recommended Standards
- N-((4-(((3-Chloroacridin-1-yl)methyl)amino)phenyl)sulfonyl)acetamide (CAS 831220-31-6)
- Rivaroxaban-d4 (CAS 1132681-38-9)
- 3-Amino-6-(2-chlorophenyl)-4-(3,4-dimethoxyphenyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 690642-63-8)
- Laropiprant-d4 (CAS 1132664-22-2)
- 1-(4-Chlorophenyl)-2,2-difluoroethyl diethyl phosphate (CAS 2108663-79-0)
- 8-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline (CAS 2235386-13-5)
- 4-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyrimidine (CAS 2839742-55-9)
- 2-(3-Amino-1h-pyrazol-1-yl)-N-(3-methylbutan-2-yl)acetamide (CAS 1249217-47-7)
- 6-methoxybenzofuran-3-carboxylic acid (CAS 29822-97-7)
- 1-Bromo-2-methyl-4-(methylsulfonyl)butane (CAS 1489667-20-0)
- 7-((4'-Cyano-[1,1'-biphenyl]-4-yl)oxy)-N-hydroxyheptanamide (CAS 191228-04-3)
- 5-(difluoromethyl)-1-(2-methylphenyl)-1H-pyrazole-4-carboxylic acid (CAS 1498346-98-7)
- Ethyl 2-(4-((tert-butoxycarbonyl)amino)phenyl)oxazole-4-carboxylate (CAS 886363-48-0)
- Tirzepatide Impurity 48 (CAS CATO-C4X-324048)
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