2-Hydroxy-5H-chromen-5-one CAS 32942-76-0
| CAS No. | 32942-76-0 |
| Molecular Formula | C9H6O3 |
| Molecular Weight | 162.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Hydroxy-5H-chromen-5-one is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-Hydroxy-5H-chromen-5-one (CAS 32942-76-0), a certified reference material (molecular formula C9H6O3, MW 162.14 g/mol) for analytical method development and quality control.
2-Hydroxy-5H-chromen-5-one (C9H6O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H6O3 |
| Molecular Weight | 162.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
Related Hydroxy Standards
- 3-Hydroxy-2-ureido-butyric acid (CAS 122331-32-2)
- 5-hydroxy-2,3-dihydro-1H-indene-1,3-dione (CAS 131977-61-2)
- 3-Hydroxy-4H-chromen-4-one (CAS 13400-26-5)
- (R)-4-Hydroxy-5-methoxy-5-oxopentanoic acid (CAS 2165747-14-6)
- 5-Hydroxy Coumarin (CAS 6093-67-0)
- 5-Hydroxy-4H-1-benzopyran-4-one (CAS 3952-69-0)
- 6-Hydroxy-4h-chromen-4-one (CAS 38445-24-8)
- 8-Hydroxy Coumarin (CAS 2442-31-1)
Recommended Standards
- 2,5-Anhydro-D-mannose (CAS 495-75-0)
- 2-Hydroxybenzofuran-3-carbaldehyde (CAS 708204-08-4)
- 2,2-Dimethyl-1,3-dinitropropane (CAS 762-98-1)
- 3-(4-Hydroxyphenyl)propiolic acid (CAS 78589-65-8)
- 5-(4-chloro-3-methylphenoxy)pentan-2-one (CAS 1225537-74-5)
- [(2-Ethylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)-methyl]amine dihydrochloride (CAS 1332528-48-9)
- Dipterocarpol (CAS 471-69-2)
- 6-Bromo-4-((3-chloro-4-fluorophenyl)amino)quinoline-3-carbonitrile (CAS 915369-04-9)
- N-Benzyl-4-hydroxy-N-[(4-methoxyphenyl)methyl]benzene-1-sulfonamide (CAS 1881295-41-5)
- 1-Phenyl-5,6-dihydrobenzo[f]isoquinoline (CAS 131372-97-9)
- 3-(Aminomethyl)-4-ethyl-6-methylpyridin-2(1H)-one hydrochloride (CAS 1346576-04-2)
- 1-(1-Bromopropan-2-yl)-2-fluorobenzene (CAS 1490333-53-3)
- 5,6,7,8-Tetrahydroquinoline (CAS 10500-57-9)
- (Des-Thr7)-Glucagon trifluoroacetate salt (CAS 1802078-28-9)
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