6-Bromo-4-((3-chloro-4-fluorophenyl)amino)quinoline-3-carbonitrile CAS 915369-04-9
| CAS No. | 915369-04-9 |
| Molecular Formula | C16H8BrClFN3 |
| Molecular Weight | 376.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Bromo-4-((3-chloro-4-fluorophenyl)amino)quinoline-3-carbonitrile (CAS 915369-04-9), molecular formula C16H8BrClFN3 and molecular weight 376.61 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Bromo-4-((3-chloro-4-fluorophenyl)amino)quinoline-3-carbonitrile (C16H8BrClFN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-Bromo-4-((3-chloro-4-fluorophenyl)amino)quinoline-3-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H8BrClFN3 |
| Molecular Weight | 376.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 3 |
Related Bromo Standards
- 6-Bromo-2-(3-methoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160265-00-8)
- 6-Bromo-2-(4-methoxyphenyl)quinoline-4-carbonyl chloride (CAS 148122-02-5)
- 6-Bromo-2-(4-chlorophenyl)-3-methylquinoline-4-carboxylic acid (CAS 438531-53-4)
- 6-Bromo-7-chloro-8-methyl-2-phenylquinoline-4-carboxylic acid (CAS 894552-27-3)
- N-(4-Bromo-2-fluorophenyl)-5-chloro-2-(methylthio)pyrimidine-4-carboxamide (CAS 898648-45-8)
- 8-(2-(4-Bromo-2-chlorophenoxy)ethyl)-1,4-dioxa-8-azaspiro[4.5]Decane (CAS 1704080-53-4)
- 3-Bromo-2-thiomorpholinomethyl benzophenone (CAS 898781-70-9)
- 3-Bromo-4-thiomorpholinomethyl benzophenone (CAS 898782-59-7)
Recommended Standards
- 959053-85-1 11-Acetoxyundecyltriethoxysilane MFCD13181918 (CAS 959053-85-1)
- tert-Butyl methyl(2,2,3,3-tetramethyl-4,7-dioxa-10-aza-3-siladodecan-12-yl)carbamate (CAS 2403639-16-5)
- N-[6-(4-fluorophenoxy)-3-pyridyl]-N'-(1,2,2-trichlorovinyl)urea (CAS 243963-25-9)
- (trans,trans)-(trans)-4-Propylcyclohexyl 4'-propyl-[1,1'-bi(cyclohexane)]-4-carboxylate (CAS 83242-83-5)
- 4-Bromo-6-(difluoromethyl)-5-(trifluoromethyl)pyridin-2-ol (CAS 1805408-28-9)
- 6-Methylpyridazine-3-carboxamide (CAS 88393-96-8)
- 2,5-Diiodobenzo[d]oxazole (CAS 1806547-33-0)
- 7-Methyl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one (CAS 1330755-99-1)
- GC376 Sodium (CAS 1416992-39-6)
- N-([1,1'-Biphenyl]-2-yl)-2-((5-(4-chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332947-88-3)
- 3-Chloro-5-(trifluoromethyl)picolinimidohydrazide (CAS 2379918-35-9)
- N-(3,4-Dichlorophenyl)-5-methyl-11-oxo-5H,5aH,6H,7H,8H,9H,11H-pyrido[2,1-b]quinazoline-3-carboxamide (CAS 1574585-05-9)
- Pcb No. 203 (CAS 52663-76-0)
- Semaglutide impurity 49 (CAS CATO-C4X-222649)
Why CATO?
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