n-(Benzo[d][1,3]dioxol-5-ylmethyl)-2-(2,4-dichlorophenoxy)propanamide CAS 329694-16-8
| CAS No. | 329694-16-8 |
| Molecular Formula | C17H15Cl2NO4 |
| Molecular Weight | 368.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of n-(Benzo[d][1,3]dioxol-5-ylmethyl)-2-(2,4-dichlorophenoxy)propanamide is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
n-(Benzo[d][1,3]dioxol-5-ylmethyl)-2-(2,4-dichlorophenoxy)propanamide (CAS 329694-16-8) is a high-purity analytical reference standard with the molecular formula C17H15Cl2NO4 and a molecular weight of 368.21 g/mol.
The molecular framework of n-(Benzo[d][1,3]dioxol-5-ylmethyl)-2-(2,4-dichlorophenoxy)propanamide (C17H15Cl2NO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), n-(Benzo[d][1,3]dioxol-5-ylmethyl)-2-(2,4-dichlorophenoxy)propanamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H15Cl2NO4 |
| Molecular Weight | 368.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related n Standards
- 2-(Benzo[d][1,3]dioxol-5-ylamino)-2-oxoethyl 5-bromofuran-2-carboxylate (CAS 386277-58-3)
- RO-4582640 (4-(8-Benzo[1,2,5]oxadiazol-5-yl-[1,7]naphthyridin-6-yl)-benzoic acid) (CAS 426268-06-6)
- 2-(Benzo[d]thiazol-2-ylthio)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 296273-03-5)
- (E)-4-(Benzo[d]thiazol-2-yl)-5-(4-methyl-3-nitrophenyl)pent-4-enoic acid (CAS 1164475-61-9)
- 1-(Benzo[d][1,3]dioxol-5-yl)-3-(4-(4-methoxyphenyl)piperazin-1-yl)propan-1-one (CAS 477328-88-4)
- n-(2-(5-(Benzo[d][1,3]dioxol-5-ylmethylene)-2,4-dioxothiazolidin-3-yl)ethyl)-2-chloroacetamide (CAS 554423-46-0)
- 4-(Benzo[d]thiazol-2-yl)-N-(6-methylbenzo[d]thiazol-2-yl)butanamide (CAS 793731-79-0)
- 2-(Benzo[d]thiazol-2-yl(methyl)amino)-1-(4-(pyridin-2-yl)piperazin-1-yl)ethan-1-one (CAS 1351602-40-8)
Recommended Standards
- N-(3,4-dichlorophenyl)-4-(furan-2-carbonyl)piperazine-1-carboxamide (CAS 305337-17-1)
- Aceclofenac Methyl Ester (Aceclofenac EP Impurity D) (CAS 139272-66-5)
- N-(3,4-dichlorophenyl)-2-(2-ethoxy-4-formylphenoxy)acetamide (CAS 247592-90-1)
- Alectinib Impurity 75 (CAS CATO-C4X-283675)
- 4-Chloro-2-cyclohexylquinazoline (CAS 284486-58-4)
- tert-Butyl 1-hydroxy-7-azaspiro[3.5]nonane-7-carboxylate (CAS 1338247-76-9)
- N-Hydroxy-4-(4-morpholinylmethyl)benzenecarboximidamide (CAS 926198-54-1)
- 3-(3-Fluoropropoxy)cyclobutanecarboxylic acid (CAS 1707568-64-6)
- Teprenone impurity 34 (CAS CATO-C4X-208134)
- 2-Chloro-4-(difluoromethyl)-6-(trifluoromethyl)nicotinic acid (CAS 1805082-64-7)
- 4-amino-1-phenylcyclohexanol (CAS 51171-78-9)
- Cellobiose Impurity 2 (CAS 6380-97-8)
- 5-(2-Aminothiazol-4-yl)-2-hydroxybenzoic acid (CAS 1416347-94-8)
- Semaglutide impurity 94 (CAS CATO-C4X-222694)
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