Alectinib Impurity 75 CAS CATO-C4X-283675
| CAS No. | CATO-C4X-283675 |
| Molecular Formula | C15H17IN2O |
| Molecular Weight | 368.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 368.21 g/mol gives Alectinib Impurity 75 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Alectinib Impurity 75 (CAS CATO-C4X-283675) is a certified pharmaceutical impurity reference standard with the molecular formula C15H17IN2O and a molecular weight of 368.21 g/mol.
Alectinib Impurity 75 (C15H17IN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Alectinib Impurity 75 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H17IN2O |
| Molecular Weight | 368.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
Related Alectinib Standards
- Alectinib Impurity 54 (CAS CATO-C4X-283654)
- Alectinib Impurity 55 (CAS CATO-C4X-283655)
- Alectinib Impurity 65 (CAS CATO-C4X-283665)
- Alectinib Impurity 2 (CAS 1256579-06-2)
- Alectinib Impurity 66 (CAS CATO-C4X-283666)
- Alectinib Impurity 53 (CAS CATO-C4X-283653)
- Alectinib impurity 28 (CAS 2412921-44-7)
- Alectinib Impurity 40 (CAS CATO-C4X-283640)
Recommended Standards
- Aceclofenac Methyl Ester (Aceclofenac EP Impurity D) (CAS 139272-66-5)
- Ethyl 7-bromo-3-(3-ethoxy-3-oxopropyl)-1H-indole-2-carboxylate, 97% (CAS 1073493-75-0)
- n-(Benzo[d][1,3]dioxol-5-ylmethyl)-2-(2,4-dichlorophenoxy)propanamide (CAS 329694-16-8)
- 1-(Tert-butyl) 2-ethyl 3-bromo-1H-indole-1,2-dicarboxylate (CAS 1135283-20-3)
- Bosutinib 4-Chloro 7-Chloropropoxy Impurity (CAS 214470-68-5)
- Iguratimod Impurity 58 (CAS CATO-C4X-182658)
- Gemcitabine Impurity 25 (CAS 166275-25-8)
- 6-Bromo-1-chloro-2,7-naphthyridine (CAS 1260670-08-3)
- 3-(3,4-Dimethoxy-phenyl)-propynoic acid (CAS 22511-06-4)
- 2-(3-Methylphenyl)-1H-imidazole (CAS 21202-37-9)
- 2-(4-Bromobenzoyl)malononitrile (CAS 1498812-40-0)
- 3-((1-Methyl-5-oxo-4,5-dihydro-1H-imidazol-2-yl)amino)benzoic acid (CAS 1707594-79-3)
- N-(2-Chlorobenzyl)-2-(4-ethyl-2,3-dioxopiperazin-1-yl)acetamide (CAS 868965-10-0)
- Fragment-[3-31]-Semaglutide (CAS CATO-C4X-2226113)
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