spiro[indene-1,4'-piperidine] CAS 33042-66-9
| CAS No. | 33042-66-9 |
| Molecular Formula | C13H21N |
| Molecular Weight | 191.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 191.31 g/mol gives spiro[indene-1,4'-piperidine] distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
spiro[indene-1,4'-piperidine] (CAS 33042-66-9), molecular formula C13H21N and molecular weight 191.31 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of spiro[indene-1,4'-piperidine] (C13H21N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), spiro[indene-1,4'-piperidine] meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H21N |
| Molecular Weight | 191.31 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Nitrogen Atoms | 1 |
Related spiro Standards
- 3H-spiro[benzo[d]thiazole-2,1'-cyclopentane] (CAS 183-31-3)
- Spiro[indoline-3,3'-thietan]-2-one (CAS 1373029-42-5)
- Spiro[benzo[b][1,4]thiazine-2,1'-cyclopropan]-3(4H)-one (CAS 681286-61-3)
- 7H-Spiro[furo[3,2-d]pyrimidine-6,4'-piperidine] (CAS 2771352-16-8)
- Spiro(benzo[1,3]dioxole-2,1'-cyclopentan)-5-ylamine (CAS 447429-09-6)
- spiro[5H-furo[3,4-b]pyridine-7,3'-tetrahydropyran] (CAS 2761389-65-3)
- Spiro[indoline-3,2'-[1,3]dioxolan]-2-one (CAS 6714-68-7)
- Spiro[chromane-2,3'-oxetan]-4-ol (CAS 1242267-65-7)
Recommended Standards
- N-Isopropyl-N-methyl-1-phenylpropan-2-amine (CAS 66514-90-7)
- Upadacitinib Impurity 167 (CAS CATO-C4X-2405167)
- n-Isopropyl-4-phenylbutan-2-amine (CAS 277302-70-2)
- N-(1-Ethylpropyl)-3，4-dimethylaniline (CAS 56038-89-2)
- 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(2-fluoro-5-nitrophenyl)urea (CAS 1022665-81-1)
- 5,6-Dimethylquinolin-8-ol (CAS 1378260-18-4)
- 5-Chloro-3-(2-iodoethyl)benzofuran (CAS 796851-79-1)
- 2-Chloro-N-(2,3-dimethoxyphenyl)quinazolin-4-amine (CAS 827030-60-4)
- N-(2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)methanesulfonamide (CAS 1204742-83-5)
- Ceritinib Impurity 82 (CAS CATO-C4X-104882)
- Methyl 2-((3-(2-(4-methoxybenzamido)ethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)butanoate (CAS 872996-34-4)
- tert-Butyl (1R,4R,5S)-5-amino-2-azabicyclo[2.2.1]heptane-2-carboxylate (CAS 1445696-33-2)
- N-(4-Cyclopropoxy-5-(dimethylamino)pyridin-3-yl)methanesulfonamide (CAS 1243451-46-8)
- Cholecystokinin Octapeptide (sulfated) (H-2060.0005) (CAS 25679-23-6)
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