2-Chloro-5-methylbenzenesulfonamide CAS 3306-63-6
| CAS No. | 3306-63-6 |
| Molecular Formula | C7H8ClNO2S |
| Molecular Weight | 205.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Chloro-5-methylbenzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-Chloro-5-methylbenzenesulfonamide (CAS 3306-63-6) is a high-purity analytical reference standard with the molecular formula C7H8ClNO2S and a molecular weight of 205.66 g/mol.
The molecular framework of 2-Chloro-5-methylbenzenesulfonamide (C7H8ClNO2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H8ClNO2S |
| Molecular Weight | 205.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 2-Chloro-5-(propan-2-yl)-1,3-thiazole-4-carboxylic acid (CAS 886360-70-9)
- 2-Chloro-6-methylbenzene-1-sulfonamide (CAS 90196-33-1)
- 2-Chloro-4-methylbenzene-1-sulfonamide (CAS 89694-89-3)
- 3-(Chloromethyl)benzenesulfonamide (CAS 943112-26-3)
- 4-Cyano-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzamide (CAS 556042-91-2)
- 6,6'-Dibromo-9,9'-diphenyl-3,3'-bicarbazole (CAS 354135-75-4)
- 2,5-Dinitropyridine (CAS 15009-92-4)
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- 2,5-Dichloro-3-(difluoromethoxy)benzoyl chloride (CAS 1806352-85-1)
- N-(4-formyl-1,3-thiazol-2-yl)-N-phenylacetamide (CAS 91973-74-9)
- 4-[2-(Benzyloxy)ethoxy]benzoic acid (CAS 223268-58-4)
- 2-(Phenylthio)cyclobutanone (CAS 60603-14-7)
- Dexmedetomidine Impurity 13 (CAS 104245-83-2)
- Acetyl-(Leu28·31)-Neuropeptide Y (24-36) (CAS 155709-24-3)
Why CATO?
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