Tadalafil Impurity 138 CAS CATO-C4X-1087138
| CAS No. | CATO-C4X-1087138 |
| Molecular Formula | C23H21N3O2 |
| Molecular Weight | 371.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Tadalafil Impurity 138 (CAS CATO-C4X-1087138), a pharmacopoeial impurity reference standard (molecular formula C23H21N3O2, MW 371.43 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C23H21N3O2, Tadalafil Impurity 138 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 371.43 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C23H21N3O2 |
| Molecular Weight | 371.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Tadalafil Standards
- Tadalafil Impurity 174 (CAS CATO-C4X-1087174)
- Tadalafil Impurity N6 (CAS 479545-76-1)
- Tadalafil Impurity 172 (CAS CATO-C4X-1087172)
- Tadalafil Impurity 81 (CAS CATO-C4X-108781)
- Tadalafil Impurity 152 (CAS CATO-C4X-1087152)
- Tadalafil Impurity 46 (CAS 1598416-07-9)
- Tadalafil Impurity 28 (CAS CATO-C4X-108728)
- Tadalafil impurity 127 (CAS CATO-C4X-1087127)
Recommended Standards
- tert-butyl 3-((quinoxalin-2-ylmethyl)carbamoyl)tetrahydropyrimidine-1(2H)-carboxylate (CAS CATO-C3D-262770)
- Azilsartan impurity 141 (CAS CATO-C4X-1096141)
- 6-Hydroxy-N-[(phenylmethoxy)carbonyl]-L-norleucine Phenylmethyl Ester 84246-49-1 Benzyl (2S)-2-carbobenzyloxyamino-6-hydroxyhexanoate (CAS 84246-49-1)
- Azilsartan Impurity 9 (CAS 136285-69-3)
- Esmolol Impurity 91 (CAS CATO-C4X-189191)
- (S)-Timolol EP Impurity C Maleate (CAS CATO-C4X-149622)
- Dobutamine Impurity 13 (CAS 82473-36-7)
- 2-(Pyridin-3-yloxy)pyridin-4-amine (CAS 181632-57-5)
- 2-(3-Aminoazetidin-1-yl)-N-cyclohexylacetamide (CAS 1339507-94-6)
- 2-Chloro-4-(heptyloxy)pyridine (CAS 1069098-66-3)
- Methyl amino(2-bromophenyl)acetate hydrochloride (CAS 1219408-44-2)
- 3-Bromo-6-iodothieno[3,2-b]thiophene (CAS 1394840-27-7)
- O-Desethyl Candesartan (CAS 168434-02-4)
- Peptide Impurity 15 (CAS 1227750-69-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com