N-(2,4-Difluorophenyl)-2-fluorobenzamide CAS 331435-72-4
| CAS No. | 331435-72-4 |
| Molecular Formula | C13H8F3NO |
| Molecular Weight | 251.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(2,4-Difluorophenyl)-2-fluorobenzamide (CAS 331435-72-4), molecular formula C13H8F3NO and molecular weight 251.20 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(2,4-Difluorophenyl)-2-fluorobenzamide (C13H8F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-(2,4-Difluorophenyl)-2-fluorobenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H8F3NO |
| Molecular Weight | 251.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- N-(2,5-Difluorophenyl)-2-fluorobenzamide (CAS 903269-74-9)
- N-(2,6-Difluorophenyl)-2-fluorobenzamide (CAS 915889-31-5)
- N-(2,6-Difluorophenyl)-4-fluorobenzamide (CAS 639811-17-9)
- N-(3,4-Difluorophenyl)-2-fluorobenzamide (CAS 330469-21-1)
- N-(3,4-Difluorophenyl)-4-fluorobenzamide (CAS 349129-89-1)
- N-(3,5-Difluorophenyl)-2-fluorobenzamide (CAS 881767-66-4)
- N-(3,5-Difluorophenyl)-4-fluorobenzamide (CAS 881767-73-3)
- 6-(2,4-Difluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 1204296-90-1)
Recommended Standards
- N-(1-Methyl-5-(5-nitrofuran-2-yl)-1H-1,2,4-triazol-3-yl)acetamide (CAS 41735-43-7)
- Methyl 5-[(4-nitro-1H-pyrazol-1-yl)methyl]-2-furoate (CAS 402614-78-2)
- Ethyl 3-cyano-2-hydroxy-6-methyl-5-nitroisonicotinate (CAS 5427-92-9)
- 8-Fluoro-7-(trifluoromethyl)-2H-thiopyrano[3,2-c]pyridin-4(3H)-one (CAS 2734925-61-0)
- 2-Iodo-n-(2,2,2-trifluoroethyl)acetamide (CAS 1343302-15-7)
- 2-Bromo-5-fluoro-4-thiocyanatoaniline (CAS 1133115-25-9)
- N-(4-bromo-3-fluorophenyl)tetrahydro-2H-thiopyran-3-amine (CAS 1489192-73-5)
- Ethyl 2-cyanohex-2-enoate (CAS 996-95-2)
- 2-(Methylsulfonyl)-6-(trifluoromethyl)thiazolo[4,5-b]pyridine (CAS 488740-94-9)
- Alogliptin Impurity 30 (CAS CATO-C4X-109930)
- 2-(3-Bromo-5-fluoro-4-nitrophenyl)acetic acid (CAS 1804407-08-6)
- Uridine Impurity 14 (CAS 872710-80-0)
- 2-Methyl-1-(pyridin-2-yl)piperazine hydrochloride (CAS 1420808-77-0)
- Pancreatic Polypeptide (rat) (CAS 90419-12-8)
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