N-(3,4-Difluorophenyl)-4-fluorobenzamide CAS 349129-89-1
| CAS No. | 349129-89-1 |
| Molecular Formula | C13H8F3NO |
| Molecular Weight | 251.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(3,4-Difluorophenyl)-4-fluorobenzamide (CAS 349129-89-1), molecular formula C13H8F3NO and molecular weight 251.20 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(3,4-Difluorophenyl)-4-fluorobenzamide (C13H8F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H8F3NO |
| Molecular Weight | 251.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- N-(2,4-Difluorophenyl)-2-fluorobenzamide (CAS 331435-72-4)
- N-(2,5-Difluorophenyl)-2-fluorobenzamide (CAS 903269-74-9)
- N-(2,6-Difluorophenyl)-2-fluorobenzamide (CAS 915889-31-5)
- N-(2,6-Difluorophenyl)-4-fluorobenzamide (CAS 639811-17-9)
- N-(3,4-Difluorophenyl)-2-fluorobenzamide (CAS 330469-21-1)
- N-(3,5-Difluorophenyl)-2-fluorobenzamide (CAS 881767-66-4)
- N-(3,5-Difluorophenyl)-4-fluorobenzamide (CAS 881767-73-3)
- 6-(2,4-Difluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 1204296-90-1)
Recommended Standards
- N-allyl-3,4-dinitrobenzamide (CAS 300679-59-8)
- Pyridin-2-yl(2-(trifluoromethyl)phenyl)methanone (CAS 898779-76-5)
- Pyridin-3-yl-[4-(trifluoromethyl)phenyl]methanone (CAS 21221-92-1)
- N-(1-Methyl-5-(5-nitrofuran-2-yl)-1H-1,2,4-triazol-3-yl)acetamide (CAS 41735-43-7)
- 5-((6-(Piperazin-1-yl)pyrimidin-4-yl)amino)pyrazine-2-carbonitrile (CAS 1137475-20-7)
- 3-(8-Amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl)cyclobutane-1,1-diol (CAS 1359704-43-0)
- 2-((tert-Butoxycarbonyl)amino)pent-4-enoicacid (CAS 119479-32-2)
- Z-D-Orn-OH (CAS 112229-51-3)
- (2-Chloro-5-ethoxyphenyl)boronic acid (CAS 913835-30-0)
- 6-Phenylpyridine-2-carbonyl chloride (CAS 1247729-30-1)
- N-(1-Ethylpyrrolidin-2-ylidene)-4-(methylamino)benzenesulfonamide (CAS 126826-54-8)
- 1-(4-Ethoxybenzyl)piperazine dihydrochloride (CAS 1609395-42-7)
- 3-(3-Bromo-4-fluorobenzyl)pyrrolidin-3-ol (CAS 1341820-63-0)
- Heptapeptide-6 (CAS CATO-CPTD788823)
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