4-[(1E)-[(3-Chloro-4-fluorophenyl)imino]methyl]phenyl 4-methylbenzoate CAS 331460-60-7
| CAS No. | 331460-60-7 |
| Molecular Formula | C21H15ClFNO2 |
| Molecular Weight | 367.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-[(1E)-[(3-Chloro-4-fluorophenyl)imino]methyl]phenyl 4-methylbenzoate (CAS 331460-60-7) is a high-purity analytical reference standard with the molecular formula C21H15ClFNO2 and a molecular weight of 367.80 g/mol.
The molecular framework of 4-[(1E)-[(3-Chloro-4-fluorophenyl)imino]methyl]phenyl 4-methylbenzoate (C21H15ClFNO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 4-[(1E)-[(3-Chloro-4-fluorophenyl)imino]methyl]phenyl 4-methylbenzoate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H15ClFNO2 |
| Molecular Weight | 367.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- (2,5-Dioxoimidazolidin-4-yl)methanesulfonic acid (CAS 58942-07-7)
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- MK-6240 Precursor (CAS 1841444-11-8)
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Why CATO?
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