4-(2-Chloro-6-fluorobenzylidene)-1,2,3,4-tetrahydroacridine-9-carboxylic acid CAS 565167-98-8
| CAS No. | 565167-98-8 |
| Molecular Formula | C21H15ClFNO2 |
| Molecular Weight | 367.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(2-Chloro-6-fluorobenzylidene)-1,2,3,4-tetrahydroacridine-9-carboxylic acid.
4-(2-Chloro-6-fluorobenzylidene)-1,2,3,4-tetrahydroacridine-9-carboxylic acid (CAS 565167-98-8), molecular formula C21H15ClFNO2 and molecular weight 367.80 g/mol, is a CATO reference standard with documented purity and traceability.
4-(2-Chloro-6-fluorobenzylidene)-1,2,3,4-tetrahydroacridine-9-carboxylic acid (C21H15ClFNO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-(2-Chloro-6-fluorobenzylidene)-1,2,3,4-tetrahydroacridine-9-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H15ClFNO2 |
| Molecular Weight | 367.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- N-(4-(N-(3,4-Dimethylisoxazol-5-yl)sulfamoyl)phenyl)-4-methoxybenzamide (CAS 301681-50-5)
- 5-(2-Bromoacetyl)-2-fluoro-4-methoxybenzonitrile (CAS 2384456-51-1)
- Methyltetrazine-Ph-PEG4-azide (CAS 1802908-04-8)
- N-Phenethyl-5,6-dihydro-4H-1,3-thiazin-2-amine (CAS 522606-42-4)
- Methyl N-(3-chloro-4-fluorophenyl)-N-(phenylsulfonyl)glycinate (CAS 863187-31-9)
- Insulin Glargine (CAS 160337-95-1)
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