2-Amino-6-(4-bromophenyl)-4-(3,4-dimethoxyphenyl)nicotinonitrile CAS 331981-00-1
| CAS No. | 331981-00-1 |
| Molecular Formula | C20H16BrN3O2 |
| Molecular Weight | 410.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Amino-6-(4-bromophenyl)-4-(3,4-dimethoxyphenyl)nicotinonitrile (CAS 331981-00-1), molecular formula C20H16BrN3O2 and molecular weight 410.26 g/mol, is a CATO reference standard with documented purity and traceability.
2-Amino-6-(4-bromophenyl)-4-(3,4-dimethoxyphenyl)nicotinonitrile (C20H16BrN3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Amino-6-(4-bromophenyl)-4-(3,4-dimethoxyphenyl)nicotinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H16BrN3O2 |
| Molecular Weight | 410.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 2-Amino-6-(4-bromophenyl)-4-(3-ethoxy-4-hydroxyphenyl)nicotinonitrile (CAS 333341-54-1)
- Ethyl 6-amino-5-cyano-4-(3-iodophenyl)-2-methyl-4H-pyran-3-carboxylate (CAS 299198-05-3)
- Methyl 2-amino-4-(3-nitrophenyl)-5-oxo-4H,5H-thiochromeno[4,3-b]pyran-3-carboxylate (CAS 939889-11-9)
- Methyl 2-amino-4-(4-nitrophenyl)-5-oxo-4H,5H-thiochromeno[4,3-b]pyran-3-carboxylate (CAS 939894-19-6)
- 4-Amino-2-propyl-1H-imidazole-5-carboxamide (CAS 90521-73-6)
- 3-Amino-6-bromo-2-((4-bromophenyl)amino)quinazolin-4(3H)-one (CAS 91539-11-6)
- Ethyl 6-amino-5-cyano-4-(4-fluorophenyl)-2-[(phenylsulfanyl)methyl]-4H-pyran-3-carboxylate (CAS 478260-22-9)
- 4-Amino-N-(4-(2-(pyridin-3-yl)thiazol-5-yl)pyrimidin-2-yl)benzenesulfonamide (CAS 1210769-98-4)
Recommended Standards
- 2-[4-(2,4-Dichlorobenzoyl)-1H-1,2,3-triazol-1-yl]-4-methyl-6-phenylpyrimidine (CAS 685109-16-4)
- 1-[(4-Bromophenyl)methoxy]-2-(4-methoxyphenyl)-1H-imidazo[4,5-b]pyridine (CAS 339027-61-1)
- 2-Chloro-3,5-dibromo-4-iodotoluene (CAS 1000572-58-6)
- (S)-4-(4-Bromo-3-cyanophenyl)-1-(tert-butoxy-carbonyl)piperazine-2-carboxylic acid (CAS 1787396-88-6)
- [1-([1,2,4]Triazolo[4,3-a]pyridin-3-ylmethyl)cyclohexyl]amine hydrochloride (CAS 1993010-50-6)
- N-[4-(2-Thienyl)-2-pyrimidinyl]-N-[3-(trifluoromethyl)phenyl]urea (CAS 439121-22-9)
- 1-(2,6-Dimethyl-3-nitrophenyl)ethanone (CAS 1415838-35-5)
- (4-(3-Ethoxy-3-oxopropyl)phenyl)boronic acid (CAS 660440-57-3)
- Methyl 2-amino-4-t-butylthiazole-5-carboxylate (CAS 478258-61-6)
- 2-(4-methylbenzoyl)-1H-indol-3-amine (CAS 1552304-61-6)
- N-(4-Methoxybenzo[d]thiazol-2-yl)-1,5-dimethyl-1H-pyrazole-3-carboxamide (CAS 1013756-86-9)
- 5-(3,4-Dihydro-2H-pyrrol-5-yl)-1H-indole (CAS 1355234-19-3)
- N-[3-(3-chloro-4-cycloÂhexylÂphenylÂ)-2-propynylÂ]-N-ethyl-cycloÂhexane amine (CAS 132173-04-7)
- Semaglutide impurity 103 (CAS 1446013-07-5)
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