2-Amino-6-(4-bromophenyl)-4-(3-ethoxy-4-hydroxyphenyl)nicotinonitrile CAS 333341-54-1
| CAS No. | 333341-54-1 |
| Molecular Formula | C20H16BrN3O2 |
| Molecular Weight | 410.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Amino-6-(4-bromophenyl)-4-(3-ethoxy-4-hydroxyphenyl)nicotinonitrile (C20H16BrN3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
2-Amino-6-(4-bromophenyl)-4-(3-ethoxy-4-hydroxyphenyl)nicotinonitrile (CAS 333341-54-1), molecular formula C20H16BrN3O2 and molecular weight 410.26 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Amino-6-(4-bromophenyl)-4-(3-ethoxy-4-hydroxyphenyl)nicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H16BrN3O2 |
| Molecular Weight | 410.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 2-Amino-6-(4-bromophenyl)-4-(3,4-dimethoxyphenyl)nicotinonitrile (CAS 331981-00-1)
- Ethyl 6-amino-5-cyano-4-(3-iodophenyl)-2-methyl-4H-pyran-3-carboxylate (CAS 299198-05-3)
- Methyl 2-amino-4-(3-nitrophenyl)-5-oxo-4H,5H-thiochromeno[4,3-b]pyran-3-carboxylate (CAS 939889-11-9)
- Methyl 2-amino-4-(4-nitrophenyl)-5-oxo-4H,5H-thiochromeno[4,3-b]pyran-3-carboxylate (CAS 939894-19-6)
- 4-Amino-2-propyl-1H-imidazole-5-carboxamide (CAS 90521-73-6)
- 3-Amino-6-bromo-2-((4-bromophenyl)amino)quinazolin-4(3H)-one (CAS 91539-11-6)
- Ethyl 6-amino-5-cyano-4-(4-fluorophenyl)-2-[(phenylsulfanyl)methyl]-4H-pyran-3-carboxylate (CAS 478260-22-9)
- 4-Amino-N-(4-(2-(pyridin-3-yl)thiazol-5-yl)pyrimidin-2-yl)benzenesulfonamide (CAS 1210769-98-4)
Recommended Standards
- 2-Chloro-3,5-dibromo-4-iodotoluene (CAS 1000572-58-6)
- 2-[4-(2,4-Dichlorobenzoyl)-1H-1,2,3-triazol-1-yl]-4-methyl-6-phenylpyrimidine (CAS 685109-16-4)
- 1,5-Dibromo-2-chloro-4-iodo-3-methylbenzene (CAS 1000573-72-7)
- 1-[(4-Bromophenyl)methoxy]-2-(4-methoxyphenyl)-1H-imidazo[4,5-b]pyridine (CAS 339027-61-1)
- 3-(tert-Butyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (CAS 1402890-07-6)
- 2-Amino-5-butyl-4-(4-methoxyphenyl)-6-phenylnicotinonitrile (CAS 331979-93-2)
- Methyl (2S,3R)-1-Boc-3-hydroxypyrrolidine-2-carboxylate (CAS 130966-46-0)
- Ethyl 2-(4-chlorophenyl)-2-methylpropanoate (CAS 56217-51-7)
- 5,6,7,8-Tetrahydroimidazo[1,2-a]pyridin-3-amine dihydrochloride (CAS 1338709-39-9)
- 2-((4,5-Dihydrothiazol-2-yl)thio)-1-(3,4-dihydroxyphenyl)ethan-1-one (CAS 1036069-26-7)
- 1-Ethyl-N-(2-methoxybenzyl)-5-methyl-1H-pyrazol-4-amine hydrochloride (CAS 1856041-48-9)
- 6,6-Dimethyl-4-oxo-4,5,6,7-tetrahydrobenzofuran-3-carboxylic acid (CAS 121625-78-3)
- 7-Chloro-4-methoxyquinoline (CAS 26707-52-8)
- Semaglutide impurity 227 (CAS CATO-C4X-2226227)
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